ArticleBlood2022
Clonal hematopoiesis is not significantly associated with COVID-19 disease severity.
Abstract read
In one paragraph
Article in Blood, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clonal hematopoiesis of indeterminate potential as a prognostic factor: a systematic review and meta-analysis.Blood advances · 2024Pooled it
- European Reference Networks - a flagship activity of the EU in the field of rare and complex diseases: from 2017 to 2025.Orphanet journal of rare diseases · 2026Review
- Clonal hematopoiesis of indeterminate potential associates with higher risk of thromboembolism in severe COVID-19.Haematologica · 2025Article
- Clonal hematopoiesis in myeloid malignancies and solid tumors.Nature cancer · 2025Review
- Single-cell multiomics reveal divergent effects of DNMT3A- and TET2-mutant clonal hematopoiesis in inflammatory response.Blood advances · 2025Article
- Review
- Clonal hematopoiesis in people with advanced HIV and associated inflammatory syndromes.JCI insight · 2024Article
- Clonal hematopoiesis and COVID-19 hospitalization in Danish adults.HemaSphere · 2024Article
- Clonal haematopoiesis, ageing and kidney disease.Nature reviews. Nephrology · 2024Review
- Article
- Clonal Hematopoiesis: Updates and Implications at the Solid Tumor-Immune Interface.JCO precision oncology · 2023Review
- Investigation of the impact of clonal hematopoiesis on severity and pathophysiology of COVID-19 in rhesus macaques.Frontiers in veterinary science · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
44 authors.
Yifan ZhouWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.ORCID 0000-0002-3538-621X
Ruba ShalhoubOffice of Biostatistics Research, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD.
Stephanie N RogersWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.ORCID 0000-0002-4563-1899
Shiqin YuTranslational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health (NIH), Bethesda, MD.
Muxin GuWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.ORCID 0000-0003-4376-795X
Margarete A FabreWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.ORCID 0000-0001-7794-610X
Pedro M QuirosWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.ORCID 0000-0002-7793-6291
Tae-Hoon ShinTranslational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health (NIH), Bethesda, MD.ORCID 0000-0002-9619-8554
Arch DiangsonCancer Molecular Diagnostics Laboratory, University of Cambridge, Cambridge, UK.
Wenhan DengCancer Molecular Diagnostics Laboratory, University of Cambridge, Cambridge, UK.
Shubha AnandCancer Molecular Diagnostics Laboratory, University of Cambridge, Cambridge, UK.
Wenhua LuEast Genomic Laboratory Hub, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK.
Matthew CullenEast Genomic Laboratory Hub, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK.
Anna L GodfreyHaematopathology and Oncology Diagnostics Service, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Jacobus PrellerJohn Farman Intensive Care Unit, Cambridge University Hospital, Cambridge, UK.ORCID 0000-0001-5706-816X
Jerome HadjadjDepartment of Internal Medicine, National Reference Center for Rare Systemic Autoimmune Diseases, Assistance Publique-Hôpitaux de Paris, APHP.CUP, Hôpital Cochin, Paris Cité University, Paris, France.
Emmanuelle JouanguyLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Aurélie CobatLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.ORCID 0000-0001-7209-6257
Laurent AbelLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Frederic Rieux-LaucatLaboratory of Immunogenetics of Pediatric Autoimmune Diseases, Université de Paris, Institut Imagine, INSERM UMR 1163, Paris, France.ORCID 0000-0001-7858-7866
Benjamin TerrierDepartment of Internal Medicine, National Reference Center for Rare Systemic Autoimmune Diseases, Assistance Publique-Hôpitaux de Paris, APHP.CUP, Hôpital Cochin, Paris Cité University, Paris, France.
Alain FischerUniversité de Paris, Institut Imagine, and Paediatric Immuno-Haematology and Rheumatology Department, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Lara NovikVaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD.
Ingelise J GordonVaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD.
Larisa StromVaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD.
Martin R GaudinskiVaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD.ORCID 0000-0002-3743-5281
Andrea LiscoHIV Pathogenesis Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD.
Irini SeretiHIV Pathogenesis Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD.
Thomas J GniadekDepartment of Pathology and Laboratory Medicine, NorthShore University Health System, Evanston, IL.
Andrea BiondiPediatric Department and Centro Tettamanti-European Reference Network PaedCan, EuroBloodNet, MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale San Gerardo, Monza, Italy.ORCID 0000-0002-6757-6173
Paolo BonfantiDepartment of Infectious Diseases, San Gerardo Hospital-University of Milano-Bicocca, Monza, Italy.ORCID 0000-0001-7289-8823
Luisa ImbertiCREA Laboratory (AIL Center for Hemato-Oncologic Research), Diagnostic Department, ASST Spedali Civili di Brescia, Brescia, Italy.ORCID 0000-0002-2075-8391
Clifton L DalgardPrimer, Uniformed Services University of the Health Sciences, Bethesda, MD.
Yu ZhangLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD.
Kerry DobbsNational Institute of Allergy and Infectious Diseases Clinical Genomics Program, NIH, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD.ORCID 0000-0002-3432-3137
Helen C SuLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD.
Luigi D NotarangeloLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD.ORCID 0000-0002-8335-0262
Colin O WuOffice of Biostatistics Research, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD.
Peter J M OpenshawNational Heart and Lung Institute, Imperial College London, Chelsea, London, UK.ORCID 0000-0002-7220-2555
Malcolm G SempleNIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.ORCID 0000-0001-9700-0418
Ziad MallatDivision of Cardiovascular Medicine, Department of Medicine, University of Cambridge, Cambridge, UK.ORCID 0000-0003-0443-7878
Kenneth BaillieRoslin Institute, University of Edinburgh, Edinburgh, UK.ORCID 0000-0001-5258-793X
Cynthia E DunbarTranslational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health (NIH), Bethesda, MD.ORCID 0000-0002-7645-838X
George S VassiliouWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.ORCID 0000-0003-4337-8022
Funding
Optimization of gene transfer safety and efficacy focusing on the NHP modelZIAHL002339 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI DUNBAR, CYNTHIA E · 2009 to 2025
$26.8MHost factors contributing to susceptibility to COVID-19 diseaseZIAAI001265 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SU, HELEN CHUN-HUI · 2020 to 2025
$9.5MCharacterization of host immune responses to SARS-CoV-2ZIAAI001270 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NOTARANGELO, LUIGI · 2020 to 2025
$1.2MRole of lymphopenia and inflammation in COVID-19 pathogenesisZIAAI001308 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SERETI, IRINI · 2020 to 2024
$743kIdentification of immunological predictors of COVID-19 clinical outcomesZIAAI001309 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI LISCO, ANDREA · 2020 to 2024
$107kBritish Heart Foundation CH/10/001/27642Cancer Research UK 23015Medical Research Council MC_PC_17230Medical Research Council MC_PC_19025Medical Research Council MC_PC_19059Wellcome Trust
Abstract
PubMed holds no abstract for this paper.
Indexed as
Clonal HematopoiesisCOVID-19Clonal EvolutionHematopoiesisHumansMutationSeverity of Illness Index
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.