Evidence map›Paper›PMID 35839336›Full record

SynthesisScandinavian journal of medicine & science in sports2022

Genetics of long-distance runners and road cyclists-A systematic review with meta-analysis.

Magdalena Johanna Konopka, Jorn Carlos Maria Leonardus van den Bunder, Gerard Rietjens, Billy Sperlich, Maurice Petrus Zeegers

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Scandinavian journal of medicine & science in sports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Association between theFrontiers in physiology · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Durability as an independent parameter of endurance performance in cycling.BMC sports science, medicine & rehabilitation · 2025
    Article
  6. Article
  7. Role of theGenes · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Magdalena Johanna KonopkaCare and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The Netherlands.ORCID https://orcid.org/0000-0002-2895-3191
Jorn Carlos Maria Leonardus van den BunderDepartment of Epidemiology, Maastricht University Medical Centre, Maastricht, The Netherlands.
Gerard RietjensDepartment of Human Physiology and Sports Medicine, Vrije Universiteit Brussel, Brussels, Belgium.
Billy SperlichIntegrative & Experimental Exercise Science & Training, Institute of Sport Science, University of Würzburg, Würzburg, Germany.
Maurice Petrus ZeegersCare and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The Netherlands.
Maastricht University Medical Centre · NLUniversity of Würzburg · DEVrije Universiteit Brussel · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this systematic review and meta-analysis was to identify the genetic variants of (inter)national competing long-distance runners and road cyclists compared with controls. The Medline and Embase databases were searched until 15 November 2021. Eligible articles included genetic epidemiological studies published in English. A homogenous group of endurance athletes competing at (inter)national level and sedentary controls were included. Pooled odds ratios based on the genotype frequency with corresponding 95% confidence intervals (95%CI) were calculated using random effects models. Heterogeneity was addressed by Q-statistics, and I

Indexed as

AthletesPolymorphism, GeneticActininBicyclingGenotypeHumansOdds RatioRunningActininACTN3 protein, humanDNAendurance athletesgenetic variantpolymorphismpredispositionsport genetics

Identifiers

PMID35839336
PMCPMC9544934
OpenAlexW4285491310

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.