SynthesisBipolar disorders2022
Smartphone-based interventions in bipolar disorder: Systematic review and meta-analyses of efficacy. A position paper from the International Society for Bipolar Disorders (ISBD) Big Data Task Force.
Synthesis in Bipolar disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Adverse Events of Mood Monitoring and Ambulatory Assessment in Depression and Bipolar Disorder: Systematic Review and Meta-Analysis.JMIR mental health · 2025Pooled it
- Smartphone-based interventions in bipolar disorder: Systematic review and meta-analyses of efficacy. A position paper from the International Society for Bipolar Disorders (ISBD) Big Data Task Force.Bipolar disorders · 2022Pooled it
- Effects of a Smartphone-Based Self-management Intervention for Individuals With Bipolar Disorder on Relapse, Symptom Burden, and Quality of Life: A Randomized Clinical Trial.JAMA psychiatry · 2023Trial
- Digital mental health tools for use by individuals in opioid use recovery: An academic scoping and commercial review.PLOS digital health · 2026Article
- Predicting Affective Episodes in Bipolar Disorder Using Statistical Process Control Analysis of GPS-Based Mobility Patterns: Quantitative Study.JMIR mHealth and uHealth · 2026Article
- Empowering Quality of Life Monitoring and Self-Management in Bipolar Disorder: Pilot Evaluation of the PolarUs App.Bipolar disorders · 2026Article
- The effect of smartphone-based monitoring and treatment including clinical feedback in progressed bipolar disorder: the SmartBipolar trial randomised controlled parallel-group trial.International journal of bipolar disorders · 2026Article
- Circadian rhythm parameters differentiate euthymic, manic and depressive mood states in bipolar disorders - an explorative pilot study.International journal of bipolar disorders · 2025Article
- What influences engagement with a bipolar disorder self-management app? A qualitative investigation of use of the PolarUs app.PLOS digital health · 2025Article
- [Scoping review on the identification and evaluation of available digital applications for bipolar disorder].Der Nervenarzt · 2025Article
- The evolving field of digital mental health: current evidence and implementation issues for smartphone apps, generative artificial intelligence, and virtual reality.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- The Inaccuracy of the Mood Disorder Questionnaire for Bipolar Disorder in a Community Sample: From the "DYMERS" Construct Toward a New Instrument for Detecting Vulnerable Conditions.Journal of clinical medicine · 2025Article
- The MinDag app for symptom monitoring and feedback to patients and clinicians during the initial treatment of bipolar disorder - a feasibility study.International journal of bipolar disorders · 2025Article
- Digital mental health treatment implementation playbook: successful practices from implementation experiences in American healthcare organizations.Frontiers in digital health · 2025Article
- Leveraging Personal Technologies in the Treatment of Schizophrenia Spectrum Disorders: Scoping Review.JMIR mental health · 2024Article
- Digital Tools to Facilitate the Detection and Treatment of Bipolar Disorder: Key Developments and Future Directions.JMIR mental health · 2024Article
- Additive effects of adjunctive app-based interventions for mental disorders - A systematic review and meta-analysis of randomised controlled trials.Internet interventions · 2024Review
- Circadian Reinforcement Therapy in Combination With Electronic Self-Monitoring to Facilitate a Safe Postdischarge Period for Patients With Major Depression: Randomized Controlled Trial.JMIR mental health · 2023Article
- Article
- A Randomized Clinical Trial of Technology-Enhanced Family-Focused Therapy for Youth in the Early Stages of Mood Disorders.JAACAP open · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe clinical effects of smartphone-based interventions for bipolar disorder (BD) have yet to be established.
objectivesTo examine the efficacy of smartphone-based interventions in BD and how the included studies reported user-engagement indicators.
methodsWe conducted a systematic search on January 24, 2022, in PubMed, Scopus, Embase, APA PsycINFO, and Web of Science. We used random-effects meta-analysis to calculate the standardized difference (Hedges' g) in pre-post change scores between smartphone intervention and control conditions. The study was pre-registered with PROSPERO (CRD42021226668).
resultsThe literature search identified 6034 studies. Thirteen articles fulfilled the selection criteria. We included seven RCTs and performed meta-analyses comparing the pre-post change in depressive and (hypo)manic symptom severity, functioning, quality of life, and perceived stress between smartphone interventions and control conditions. There was significant heterogeneity among studies and no meta-analysis reached statistical significance. Results were also inconclusive regarding affective relapses and psychiatric readmissions. All studies reported positive user-engagement indicators.
conclusionWe did not find evidence to support that smartphone interventions may reduce the severity of depressive or manic symptoms in BD. The high heterogeneity of studies supports the need for expert consensus to establish ideally how studies should be designed and the use of more sensitive outcomes, such as affective relapses and psychiatric hospitalizations, as well as the quantification of mood instability. The ISBD Big Data Task Force provides preliminary recommendations to reduce the heterogeneity and achieve more valid evidence in the field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.