Evidence map›Paper›PMID 35839153›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2022

Sex matters in the aging heart: implications for antifibrotic therapies.

Alexandra M Garvin, Taben M Hale

Abstract readEditorialComment
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Sex as a biological variable for cardiovascular physiology.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  4. Fibroblasts under pressure: cardiac fibroblast responses to hypertension and antihypertensive therapies.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  5. Guidelines on the use of sex and gender in cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Alexandra M GarvinDepartment of Basic Medical Sciences, College of Medicine-Phoenix, University of Arizona, Phoenix, Arizona.ORCID 0000-0002-5784-5587
Taben M HaleDepartment of Basic Medical Sciences, College of Medicine-Phoenix, University of Arizona, Phoenix, Arizona.ORCID 0000-0002-5066-1216

Funding

PHYSIOLOGYT32HL007249 · NHLBI · UNIVERSITY OF ARIZONA · PI Brett A Colson, JOHN P KONHILAS · 1985 to 2026
$12.5M
Targeting Resident Cardiac Fibroblast Subpopulations for Protection Against FibrosisR01HL153112 · NHLBI · UNIVERSITY OF ARIZONA · PI HALE, TABEN M. · 2022 to 2025
$1.9M
NHLBI NIH HHS R01 HL153112NHLBI NIH HHS T32 HL007249
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgingHeartAnimalsFemaleFibrosisMaleMicePhenotypeagingcardiac fibrosisextracellular matrixfibroblastsex differences

Identifiers

PMID35839153
PMCPMC9342135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.