ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2022
Metabolic activation of tachysterol
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In one paragraph
Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 56 citations in OpenAlex.
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- Neuro-immuno-endocrinology of the skin: how environment regulates body homeostasis.Nature reviews. Endocrinology · 2025Review
- Melatonin and the Skin: Current Progress and Perspectives for Human Health.The Journal of investigative dermatology · 2025Review
- Beneficial health effects of ultraviolet radiation: expert review and conference report.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025Review
- Melatonin and vitamin D as potential synergistic adjuvants for cancer therapy (Review).International journal of oncology · 2024Review
- The Role of Retinoic-Acid-Related Orphan Receptor (RORs) in Cellular Homeostasis.International journal of molecular sciences · 2024Review
- Evolutionary formation of melatonin and vitamin D in early life forms: insects take centre stage.Biological reviews of the Cambridge Philosophical Society · 2024Review
- Biological Effects of CYP11A1-Derived Vitamin D and Lumisterol Metabolites in the Skin.The Journal of investigative dermatology · 2024Review
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- From 7-dehydrocholesterol to vitamin DFood chemistry: X · 2024Article
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- Vitamin D: An Essential Nutrient in the Dual Relationship between Autoimmune Thyroid Diseases and Celiac Disease-A Comprehensive Review.Nutrients · 2024Review
- Effect of exogenous calcitriol on myopia development and axial length in guinea pigs with form deprivation myopia.Scientific reports · 2024Article
- Photo-neuro-immuno-endocrinology: How the ultraviolet radiation regulates the body, brain, and immune system.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Dissection of an impact of VDR and RXRA on the genomic activity of 1,25(OH)Molecular and cellular endocrinology · 2024Article
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- Nutritional Supplements for Skin Health-A Review of What Should Be Chosen and Why.Medicina (Kaunas, Lithuania) · 2023Review
- Recent Advances in Vitamin D Biology: Something New under the Sun.The Journal of investigative dermatology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 5 institutions in 3 countries.
Andrzej T SlominskiDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-8963-3995
Tae-Kang KimDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Radomir M SlominskiDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Yuwei SongDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Zorica JanjetovicDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Ewa PodgorskaDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Sivani B ReddyDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Yuhua SongDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Chander RamanDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Edith K Y TangSchool of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia.
Adrian FabisiakDepartment of Chemistry, University of Warsaw, Warsaw, Poland.
Pawel BrzeminskiDepartment of Chemistry, University of Warsaw, Warsaw, Poland.
Rafal R SicinskiDepartment of Chemistry, University of Warsaw, Warsaw, Poland.
Venkatram AtigaddaDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Anton M JettenCell Biology Section, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA.ORCID 0000-0003-0954-4445
Michael F HolickDepartment of Medicine, Boston University, Boston, Massachusetts, USA.
Robert C TuckeySchool of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia.
University of Alabama at Birmingham · USUniversity of Warsaw · PLThe University of Western Australia · AUBoston University · USNational Institutes of Health · US
Funding
XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9MNuclear receptors: action, functions, and roles in diseaseZIAES101586 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI JETTEN, ANTON M · 2009 to 2025
$13.5MMechanism of action and function of novel secosteroid 20(OH)D3 in the skinR01AR073004 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ANDRZEJ T SLOMINSKI · 2018 to 2026
$2.9MSignificance of metabolic activation of lumisterol in the skinR01AR071189 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SLOMINSKI, ANDRZEJ T · 2017 to 2021
$1.6MCanonical and non-canonical vitamin D activation pathways in systemic lupusR21AI149267 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RAMAN, CHANDER, SLOMINSKI, ANDRZEJ T · 2020 to 2021
$408kCYP11A1-derived secosteroids as therapeutic agents in UVB induced skin cancerI01BX004293 · VA · BIRMINGHAM VA MEDICAL CENTER · PI SLOMINSKI, ANDRZEJ T · 2019 to 2025
–BLRD VA I01 BX004293NCI NIH HHS P30 CA013148NIAID NIH HHS R21 AI149267NIAMS NIH HHS R01 AR071189NIAMS NIH HHS R01 AR073004
Abstract
CYP11A1 and CYP27A1 hydroxylate tachysterol
Indexed as
CholecalciferolPPAR gammaReceptors, CalcitriolActivation, MetabolicHumansLiver X ReceptorsMolecular Docking SimulationReceptors, Aryl HydrocarbonCholecalciferolLiver X ReceptorsPPAR gammaprevitamin D(3)Receptors, Aryl HydrocarbonReceptors, CalcitriolVDR protein, humanCYP11A1keratinocytesreceptorsskintachysteroltachysterol hydroxymetabolitesultraviolet Bvitamin D3
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.