Evidence map›Paper›PMID 35838868›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2022

Anastomotic biliary stricture following liver transplantation and management analysis: 15 years of experience at a high-volume transplant center.

Omid Eslami, Bobak Moazzami, Zohyra E Zabala, Nader Roushan, Habibollah Dashti, Nasir Fakhar, Hazhir Saberi, Ali Jafarian, Mohssen Nassiri Toosi

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Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Biliary anastomotic strictures are recipient, not donor-related complications; deserve international guidelines for clinical diagnosis and management.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Omid EslamiLiver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Bobak MoazzamiDivision of Endocrinology, Metabolism and Lipids, Emory University School of Medicine, Atlanta, GA, USA. bobak.moazzami@emory.edu.
Zohyra E ZabalaDivision of Endocrinology, Metabolism and Lipids, Emory University School of Medicine, Atlanta, GA, USA.
Nader RoushanLiver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Habibollah DashtiLiver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Nasir FakharLiver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Hazhir SaberiDepartment of Radiology, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ali JafarianLiver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mohssen Nassiri ToosiLiver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran. nasirito@sina.tums.ac.ir.
Tehran University of Medical Sciences · IREmory University · USImam Khomeini Hospital · IRKerman University of Medical Sciences · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe occurrence of anastomotic biliary stricture (BS) remains an essential issue following liver transplantation (LT). The present study aimed to compare our findings regarding the incidence of anastomotic BS to what is known.

methodsThe present study is a single-center, retrospective cohort study of a total number of 717 consecutive patients (426 men and 291 women) who had undergone LT from January 2001 to March 2016. Multivariable Cox regression analysis was conducted to evaluate the risk factors associated with anastomotic BS development.

resultsPost-transplant anastomotic BS developed in 70 patients (9.8%). In the Cox multivariate analysis (a stepwise forward conditional method), factors including biliary leak (hazard ratio [HR]: 6.61, 95% confidence interval [CI]: 3.08-17.58, p < 0.001), hepatic artery thrombosis (HR: 2.29, 95% CI: 1.03-5.88; p = 0.003), and acute rejection (HR: 2.18, 95% CI: 1.16-3.37; p = 0.006) were identified as independent risk factors for the development of anastomotic BS. Surgery in 6 cases (66.7%), followed by endoscopic retrograde cholangiopancreatography (ECRP) with a metal stent in 18 cases (62.1%), percutaneous transhepatic biliary drainage in 9 (20.9%), and ERCP with a single plastic stent in 8 (18.2%), had the highest effectiveness rates in the management of BS, respectively.

conclusionsRisk factors including biliary leak, hepatic artery thrombosis, and acute rejection were independently associated with an anastomotic BS. ERCP with a metal stent may be considered as an effective treatment procedure with a relatively low complication rate in the management of benign post-LT anastomotic BS.

Indexed as

CholestasisLiver TransplantationCholangiopancreatography, Endoscopic RetrogradeConstriction, PathologicFemaleHumansMalePostoperative ComplicationsRetrospective StudiesTreatment OutcomeBile ductsBiliary complicationBiliary stentBiliary stricturesCholestasisEndoscopic retrograde cholangiographyERCPJaundiceLiver transplantsPatient survivalPost-liver transplant biliary stricturesRetrograde cholangiopancreatography

Identifiers

PMID35838868
OpenAlexW4285589291

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.