Evidence map›Paper›PMID 35838531›Full record

ReviewRadiology. Imaging cancer2022

Animal Models of Hepatocellular Carcinoma for Local-Regional Intraarterial Therapies.

Vishnu M Chandra, Luke R Wilkins, David L Brautigan

Abstract readReview
In one paragraph

Review in Radiology. Imaging cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vishnu M ChandraFrom the Department of Radiology and Medical Imaging (V.M.C., L.R.W.) and Department of Microbiology, Immunology, and Cancer Biology (D.L.B.), University of Virginia Health Systems, 1215 Lee St, PO Box 800170, Charlottesville, VA 22908.ORCID 0000-0002-6580-0792
Luke R WilkinsFrom the Department of Radiology and Medical Imaging (V.M.C., L.R.W.) and Department of Microbiology, Immunology, and Cancer Biology (D.L.B.), University of Virginia Health Systems, 1215 Lee St, PO Box 800170, Charlottesville, VA 22908.ORCID 0000-0003-0702-0824
David L BrautiganFrom the Department of Radiology and Medical Imaging (V.M.C., L.R.W.) and Department of Microbiology, Immunology, and Cancer Biology (D.L.B.), University of Virginia Health Systems, 1215 Lee St, PO Box 800170, Charlottesville, VA 22908.ORCID 0000-0003-1687-5250

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal models play a crucial role in developing and testing new therapies for hepatocellular carcinoma (HCC), providing preclinical evidence prior to exploring human safety and efficacy outcomes. The interventional radiologist must weigh the advantages and disadvantages of various animal models available when testing a new local-regional therapy. This review highlights the currently available animal models for testing local-regional therapies for HCC and details the importance of considering animal genetics, tumor biology, and molecular mechanisms when ultimately choosing an animal model.

Indexed as

Carcinoma, HepatocellularChemoembolization, TherapeuticLiver NeoplasmsAnimalsHumansModels, AnimalTomography, X-Ray ComputedAnimal StudiesChemoembolizationInterventional-VascularLiverMolecular Imaging-CancerMolecular Imaging-Clinical Translation

Identifiers

PMID35838531
PMCPMC9358488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.