Evidence map›Paper›PMID 35838349›Full record

ArticleeLife2022

A non-transcriptional function of Yap regulates the DNA replication program in

Rodrigo Meléndez García, Olivier Haccard, Albert Chesneau, Hemalatha Narassimprakash, Jérôme Roger, Muriel Perron, Kathrin Marheineke, Odile Bronchain

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. On the mechanisms of epidermal stemness and differentiation.NPJ systems biology and applications · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rodrigo Meléndez García *Paris-Saclay Institute of Neuroscience, CNRS, Université Paris-Saclay, CERTOFrance, Saclay, France.
Olivier Haccard *Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.ORCID 0000-0002-4305-2746
Albert ChesneauParis-Saclay Institute of Neuroscience, CNRS, Université Paris-Saclay, CERTOFrance, Saclay, France.
Hemalatha NarassimprakashUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.
Jérôme RogerParis-Saclay Institute of Neuroscience, CNRS, Université Paris-Saclay, CERTOFrance, Saclay, France.
Muriel PerronParis-Saclay Institute of Neuroscience, CNRS, Université Paris-Saclay, CERTOFrance, Saclay, France.ORCID 0000-0002-1558-8236
Kathrin MarheinekeUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.ORCID 0000-0002-1514-0167
Odile BronchainParis-Saclay Institute of Neuroscience, CNRS, Université Paris-Saclay, CERTOFrance, Saclay, France.ORCID 0000-0001-8932-8907
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In multicellular eukaryotic organisms, the initiation of DNA replication occurs asynchronously throughout S-phase according to a regulated replication timing program. Here, using

Indexed as

Replication OriginTelomere-Binding ProteinsAnimalsDNA ReplicationDNA Replication TimingS PhaseXenopus laevisTelomere-Binding Proteinscell biologydevelopmental biologyDNA replicationhippo/yap pathwayretinal stem cellsRif1trim-awayxenopus

Identifiers

PMID35838349
PMCPMC9328763
OpenAlexW4285589492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.