Evidence map›Paper›PMID 35838228›Full record

ArticleeLife2022

Phosphoregulation accommodates Type III secretion and assembly of a tether of ER-

Rachel J Ende, Rebecca L Murray, Samantha K D'Spain, Isabelle Coppens, Isabelle Derré

Abstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Inclusion Membrane Proteins ofMicroorganisms · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
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  7. Review
  8. Review
  9. Article
  10. TheProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Establishing the intracellular niche of obligate intracellular vacuolar pathogens.Frontiers in cellular and infection microbiology · 2023
    Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rachel J Ende *Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, United States.ORCID 0000-0002-1625-5433
Rebecca L Murray *Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, United States.
Samantha K D'SpainDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, United States.
Isabelle CoppensDepartment of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, United States.
Isabelle DerréDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, United States.ORCID 0000-0002-7055-4346

Funding

Regulation and composition of ER-inclusion contacts at key stages of the Chlamydia developmental cycleR21AI166237 · NIAID · UNIVERSITY OF VIRGINIA · PI DERRE, ISABELLE · 2022 to 2023
$425k
NIAID NIH HHS R21 AI166237
6 · The paper itself

Abstract

Membrane contact sites (MCS) are crucial for nonvesicular trafficking-based interorganelle communication. Endoplasmic reticulum (ER)-organelle tethering occurs in part through the interaction of the ER resident protein VAP with FFAT motif-containing proteins. FFAT motifs are characterized by a seven amino acidic core surrounded by acid tracks. We have previously shown that the human intracellular bacterial pathogen

Indexed as

ChlamydiaVesicular Transport ProteinsAmino Acid MotifsEndoplasmic ReticulumHumansMembrane ProteinsProtein BindingSerineMembrane ProteinsSerineVesicular Transport Proteinscell biologychlamydia inclusion membrane protein incvChlamydia trachomatisCK2endoplasmic reticulumFFATinfectious diseasemembrane contact sitesmicrobiologyVAP

Identifiers

PMID35838228
PMCPMC9286742

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.