Evidence map›Paper›PMID 35838180›Full record

ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2022

Collagen X Biomarker (CXM), Linear Growth, and Bone Development in a Vitamin D Intervention Study in Infants.

Helena H Hauta-Alus, Elisa M Holmlund-Suila, Saara M Valkama, Maria Enlund-Cerullo, Jenni Rosendahl, Ryan F Coghlan, Sture Andersson, Outi Mäkitie

Open access · hybridAbstract read
In one paragraph

Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Helena H Hauta-AlusChildren's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0002-3487-7834
Elisa M Holmlund-SuilaChildren's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Saara M ValkamaChildren's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0002-1096-7704
Maria Enlund-CerulloChildren's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0001-9057-1840
Jenni RosendahlChildren's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Ryan F CoghlanShriners Hospital for Children, Portland, OR, USA.
Sture AnderssonChildren's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0001-9026-412X
Outi MäkitieChildren's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0002-4547-001X
University of Helsinki · FIKarolinska University Hospital · SEShriners Hospitals for Children - Portland · US

Funding

Academy of FinlandA Special Governmental Subsidy for Clinical ResearchFinska LäkaresällskapetFolkhälsanin TutkimussäätiöFoundation for Pediatric ResearchJuho Vainio FoundationNovo Nordisk FoundationPäivikki ja Sakari Sohlbergin SäätiöSigrid Jusélius FoundationThe Finnish Medical Foundation
6 · The paper itself

Abstract

Collagen X biomarker (CXM) is suggested to be a biomarker of linear growth velocity. However, early childhood data are limited. This study examines the relationship of CXM to the linear growth rate and bone development, including the possible modifying effects of vitamin D supplementation. We analyzed a cohort of 276 term-born children participating in the Vitamin D Intervention in Infants (VIDI) study. Infants received 10 μg/d (group-10) or 30 μg/d (group-30) vitamin D

Indexed as

Bone DevelopmentVitamin DBiomarkersBone DensityChildChild, PreschoolCholecalciferolCollagenHumansInfantBiomarkersCholecalciferolCollagenVitamin DBONECOLLAGEN X BIOMARKEREARLY CHILDHOODLINEAR GROWTHVITAMIN D

Identifiers

PMID35838180
PMCPMC9544705
OpenAlexW4285588970

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.