Evidence map›Paper›PMID 35837859›Full record

ArticleEnvironmental microbiology2022

Infection-competent monkeypox virus contamination identified in domestic settings following an imported case of monkeypox into the UK.

Barry Atkinson, Christopher Burton, Thomas Pottage, Katy-Anne Thompson, Didier Ngabo, Ant Crook, James Pitman, Sian Summers, Kuiama Lewandowski, Jenna Furneaux and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Monkeypox-Induced Myocarditis: A Systematic Review.Current problems in cardiology · 2023
    Pooled it
  3. How can imported monkeypox break the borders? A rapid systematic review.Comparative immunology, microbiology and infectious diseases · 2023
    Pooled it
  4. Article
  5. Article
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  7. Air and surface sampling for clade Ib monkeypox virus in United Kingdom hospitals, 2024 to 2025.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Barry AtkinsonResearch and Evaluation, UK Health Security Agency, Porton Down, Salisbury, UK.ORCID 0000-0002-1348-7204
Christopher BurtonHigh Containment Microbiology, UK Health Security Agency, Porton Down, Salisbury, UK.
Thomas PottageResearch and Evaluation, UK Health Security Agency, Porton Down, Salisbury, UK.
Katy-Anne ThompsonResearch and Evaluation, UK Health Security Agency, Porton Down, Salisbury, UK.
Didier NgaboResearch and Evaluation, UK Health Security Agency, Porton Down, Salisbury, UK.
Ant CrookResearch and Evaluation, UK Health Security Agency, Porton Down, Salisbury, UK.
James PitmanHigh Containment Microbiology, UK Health Security Agency, Porton Down, Salisbury, UK.
Sian SummersHigh Containment Microbiology, UK Health Security Agency, Porton Down, Salisbury, UK.
Kuiama LewandowskiResearch and Evaluation, UK Health Security Agency, Porton Down, Salisbury, UK.
Jenna FurneauxRare and Imported Pathogens Laboratory, UK Health Security Agency, Porton Down, Salisbury, UK.
Katherine DaviesResearch and Evaluation, UK Health Security Agency, Porton Down, Salisbury, UK.
Timothy BrooksRare and Imported Pathogens Laboratory, UK Health Security Agency, Porton Down, Salisbury, UK.
Allan M BennettResearch and Evaluation, UK Health Security Agency, Porton Down, Salisbury, UK.
Kevin S RichardsHigh Containment Microbiology, UK Health Security Agency, Porton Down, Salisbury, UK.
Defence Science and Technology Laboratory · GBOxford Brookes University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An imported case of monkeypox was diagnosed in December 2019 in a traveller returning from Nigeria to the UK. Subsequently, environmental sampling was performed at two adjoining single-room residences occupied by the patient and their sibling. Monkeypox virus DNA was identified in multiple locations throughout both properties, and monkeypox virus was isolated from several samples 3 days after the patient was last in these locations. Positive samples were identified following the use of both vacuum and surface sampling techniques; these methodologies allowed for environmental analysis of potentially contaminated porous and non-porous surfaces via real-time quantitative reverse transcriptase PCR analysis in addition to viral isolation to confirm the presence of infection-competent virus. This report confirms the potential for infection-competent monkeypox virus to be recovered in environmental settings associated with known positive cases and the necessity for rapid environmental assessment to reduce potential exposure to close contacts and the general public. The methods adopted in this investigation may be used for future confirmed cases of monkeypox in order to establish levels of contamination, confirm the presence of infection-competent material and to identify locations requiring additional cleaning.

Indexed as

Monkeypox virusMpox, MonkeypoxDisease OutbreaksDNA, ViralHumansUnited KingdomDNA, Viral

Identifiers

PMID35837859
PMCPMC9796424
OpenAlexW4285591800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.