Evidence map›Paper›PMID 35837832›Full record

ReviewExperimental dermatology2022

Novel aspects of Raman spectroscopy in skin research.

Dominique Lunter, Victoria Klang, Dorottya Kocsis, Zsófia Varga-Medveczky, Szilvia Berkó, Franciska Erdő

Abstract readReview
In one paragraph

Review in Experimental dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dominique LunterDepartment of Pharmaceutical Technology, Institute of Pharmacy and Biochemistry, Eberhard Karls University of Tübingen, University of Tübingen, Tübingen, Germany.
Victoria KlangDivision of Pharmaceutical Technology and Biopharmaceutics, Department of Pharmaceutical Sciences, Faculty of Life Sciences, University of Vienna, Vienna, Austria.ORCID 0000-0003-2561-4378
Dorottya KocsisFaculty of Information Technology and Bionics, Pázmány Péter Catholic University, Budapest, Hungary.ORCID 0000-0001-7908-3248
Zsófia Varga-MedveczkyFaculty of Information Technology and Bionics, Pázmány Péter Catholic University, Budapest, Hungary.
Szilvia BerkóInstitute of Pharmaceutical Technology and Regulatory Affairs, Faculty of Pharmacy, University of Szeged, Szeged, Hungary.
Franciska ErdőFaculty of Information Technology and Bionics, Pázmány Péter Catholic University, Budapest, Hungary.ORCID 0000-0001-6265-3777

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The analytical technology of Raman spectroscopy has an almost 100-year history. During this period, many modifications and developments happened in the method like discovery of laser, improvements in optical elements and sensitivity of spectrometer and also more advanced light detection systems. Many types of the innovative techniques appeared (e.g. Transmittance Raman spectroscopy, Coherent Raman Scattering microscopy, Surface-Enhanced Raman scattering and Confocal Raman spectroscopy/microscopy). This review article gives a short description about these different Raman techniques and their possible applications. Then, a short statistical part is coming about the appearance of Raman spectroscopy in the scientific literature from the beginnings to these days. The third part of the paper shows the main application options of the technique (especially confocal Raman spectroscopy) in skin research, including skin composition analysis, drug penetration monitoring and analysis, diagnostic utilizations in dermatology and cosmeto-scientific applications. At the end, the possible role of artificial intelligence in Raman data analysis and the regulatory aspect of these techniques in dermatology are briefly summarized. For the future of Raman Spectroscopy, increasing clinical relevance and in vivo applications can be predicted with spreading of non-destructive methods and appearance with the most advanced instruments with rapid analysis time.

Indexed as

Artificial IntelligenceSpectrum Analysis, RamanMicroscopy, ConfocalSkinSkin Absorptionartificial intelligencecosmetoscienceRaman spectroscopyskin compositionskin diagnosticsskin researchtopical drug penetration

Identifiers

PMID35837832
PMCPMC9545633

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.