Evidence map›Paper›PMID 35837474›Full record

ReviewFrontiers in cellular and infection microbiology2022

Next-Generation Probiotic Therapy to Protect the Intestines From Injury.

Mecklin V Ragan, Samantha J Wala, Steven D Goodman, Michael T Bailey, Gail E Besner

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Gut microbes · 2025
    Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Therapeutic Potential ofFoods (Basel, Switzerland) · 2024
    Article
  9. Bibliometric analysis of intestinal microbiota and lung diseases.Frontiers in cellular and infection microbiology · 2024
    Article
  10. Preventive effect ofFrontiers in microbiology · 2024
    Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mecklin V RaganCenter for Perinatal Research, Department of Pediatric Surgery, Columbus, OH, United States.
Samantha J WalaCenter for Perinatal Research, Department of Pediatric Surgery, Columbus, OH, United States.
Steven D GoodmanNationwide Children's Hospital, The Ohio State University, Columbus, OH, United States.
Michael T BaileyNationwide Children's Hospital, The Ohio State University, Columbus, OH, United States.
Gail E BesnerCenter for Perinatal Research, Department of Pediatric Surgery, Columbus, OH, United States.
The Ohio State University · US

Funding

Tunable Native Probiotic Formulations for the Treatment of NEC.R01GM123482 · NIGMS · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI BAILEY, MICHAEL T, BESNER, GAIL E · 2017 to 2020
$1.8M
NIGMS NIH HHS R01 GM123482
6 · The paper itself

Abstract

Probiotics are live microorganisms that, when administered in adequate amounts, provide health benefits to the host. Some strains of the probiotic

Indexed as

Clostridioides difficileClostridium InfectionsEnterocolitis, NecrotizingLimosilactobacillus reuteriProbioticsAnimalsHumansInfant, NewbornIntestinesMiceRatsbiofilmClostridioides difficileLactobacillus reuterinecrotizing enterocolitisprobiotics

Identifiers

PMID35837474
PMCPMC9273849
OpenAlexW4283659326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.