Evidence map›Paper›PMID 35837429›Full record

ArticleJournal of craniovertebral junction & spine

Mohammad Humayun Rashid, Mohammad Nazrul Hossain, Nazmin Ahmed, Raad Kazi, Gianluca Ferini, Paolo Palmisciano, Gianluca Scalia, Giuseppe Emmanuele Umana, Samer S Hoz, Bipin Chaurasia

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of craniovertebral junction & spine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Lumbar Spine Mucormycosis Mimicking Pott's Spine: A Case Report.Case reports in infectious diseases · 2026
    Article
  4. Lumbar postoperativeFrontiers in medicine · 2026
    Article
  5. Review
  6. Article
  7. Spinal infection caused byFrontiers in medicine · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Mohammad Humayun RashidDepartment of Neurosurgery, H Ibrahim Cardiac Hospital and Research Institute, Dhaka, Bangladesh.
Mohammad Nazrul HossainDepartment of Neurosurgery, H Ibrahim Cardiac Hospital and Research Institute, Dhaka, Bangladesh.
Nazmin AhmedDepartment of Neurosurgery, H Ibrahim Cardiac Hospital and Research Institute, Dhaka, Bangladesh.
Raad KaziDepartment of Neurosurgery, H Ibrahim Cardiac Hospital and Research Institute, Dhaka, Bangladesh.
Gianluca FeriniDepartment of Radiation Oncology, REM Radioterapia Srl, Viagrande, Italy.
Paolo PalmiscianoDepartment of Neurosurgery, Trauma Center, Gamma Knife Center, Cannizzaro Hospital, Catania, Italy.
Gianluca ScaliaDepartment of Neurosurgery, Highly Specialized Hospital and of National Importance "Garibaldi", Catania, Italy.
Giuseppe Emmanuele UmanaDepartment of Neurosurgery, Trauma Center, Gamma Knife Center, Cannizzaro Hospital, Catania, Italy.
Samer S HozDepartment of Neurosurgery, Neurosurgery Teaching Hospital, Baghdad, Iraq.
Bipin ChaurasiaDepartment of Neurosurgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
Ibrahim Cardiac Hospital & Research Institute · BDOspedale Cannizzaro · ITBaghdad Medical City · IQBangabandhu Sheikh Mujib Medical University · BDOspedale Garibaldi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillus spinal epidural abscess (ASEA) is a rare entity that may mimic Pott's paraplegia as it commonly affects immunocompromised patients. We present one institutional case of ASEA with concomitant review of the literature. A 58-year-old female presented with intermittent low back pain for 10 years recently aggravated and with concurrent spastic paraparesis, fever, and weight loss. Emergent magnetic resonance imaging (MRI) showed T11-T12 epidural abscess with discitis and osteomyelitis. After empirical treatment with antibiotics, computed tomography-guided, percutaneous biopsy with drainage was performed, showing granulomatous tubercular-like collection. Antitubercular therapy was initiated, but after 1 month, the patient's condition deteriorated. Repeat MRI showed growth of the spinal epidural abscess with significant cord compression and vertebral osteomyelitis. T11-T12 laminectomy and tissue removal were performed with a posterior midline approach. Tissue histopathology showed necrotic debris colonies of Aspergillus spp. Antifungal therapy was started, and the patient rapidly improved. ASEA may mimic Pott's disease at imaging, leading to immediate start of antitubercular treatment without prior biopsy, leading to severe worsening of patients' clinical status. Cases of ASEA should be considered at pretreatment planning, opting for biopsy confirmation before treatment initiation so to prevent the occurrence of fatal infection-related complications.

Indexed as

Aspergillus infectionspinal epidural abscessspine infectionspine osteomyelitis

Identifiers

PMID35837429
PMCPMC9274668
OpenAlexW4285123150

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.