Evidence map›Paper›PMID 35837411›Full record

ArticleFrontiers in immunology2022

Altered Circulating Immune Cell Distribution in Traumatic Spinal Cord Injury Patients in Relation to Clinical Parameters.

Judith Fraussen, Lien Beckers, Charlotte C M van Laake-Geelen, Bart Depreitere, Jens Deckers, Erwin M J Cornips, Dieter Peuskens, Veerle Somers

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Peripheral Immune Remodeling After Spinal Cord Injury: Marked by Expansion of CD38Neurology(R) neuroimmunology & neuroinflammation · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Judith FraussenDepartment of Immunology and Infection, Biomedical Research Institute, Hasselt University, Hasselt, Belgium.
Lien BeckersDepartment of Immunology and Infection, Biomedical Research Institute, Hasselt University, Hasselt, Belgium.
Charlotte C M van Laake-GeelenAdelante Centre of Expertise in Rehabilitation and Audiology, Hoensbroek, Netherlands.
Bart DepreitereDivision of Neurosurgery, University Hospitals Leuven, Leuven, Belgium.
Jens DeckersDepartment of Neurosurgery, Algemeen Ziekenhuis (AZ) Turnhout, Turnhout, Belgium.
Erwin M J CornipsDepartment of Neurosurgery, Ziekenhuis Oost-Limburg, Genk, Belgium.
Dieter PeuskensDepartment of Neurosurgery, Ziekenhuis Oost-Limburg, Genk, Belgium.
Veerle SomersDepartment of Immunology and Infection, Biomedical Research Institute, Hasselt University, Hasselt, Belgium.
Hasselt University · BEZiekenhuis Oost-Limburg · BEAZ Turnhout · BEKU Leuven · BEMaastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following a spinal cord injury (SCI), an inflammatory immune reaction is triggered which results in advanced secondary tissue damage. The systemic post-SCI immune response is poorly understood. This study aimed to extensively analyse the circulating immune cell composition in traumatic SCI patients in relation to clinical parameters. High-dimensional flow cytometry was performed on peripheral blood mononuclear cells of 18 traumatic SCI patients and 18 healthy controls to determine immune cell subsets. SCI blood samples were collected at multiple time points in the (sub)acute (0 days to 3 weeks post-SCI, (s)aSCI) and chronic (6 to >18 weeks post-SCI, cSCI) disease phase. Total and CD4

Indexed as

Spinal Cord InjuriesSpinal InjuriesB-LymphocytesHumansImmunoglobulin MInflammationLeukocytes, MononuclearImmunoglobulin MB cellsCD74high-dimensional flow cytometryimmune profilingtraumatic spinal cord injury

Identifiers

PMID35837411
PMCPMC9273975
OpenAlexW4283646985

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.