Evidence map›Paper›PMID 35837094›Full record

ArticleFrontiers in oncology2022

Molecular Characterization of the Tumor Microenvironment in Renal Medullary Carcinoma.

David S Tourigny, Mark Zucker, Minsoo Kim, Paul Russo, Jonathan Coleman, Chung-Han Lee, Maria I Carlo, Ying-Bei Chen, A Ari Hakimi, Ritesh R Kotecha and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. CA-125 as a Biomarker in Renal Medullary Carcinoma: Integrated Molecular Profiling, Functional Characterization, and Prospective Clinical Validation.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Article
  5. Review
  6. Ferroptosis as an emerging target in sickle cell disease.Current research in toxicology · 2024
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

David S TourignyIrving Institute for Cancer Dynamics, Columbia University, New York, NY, United States.
Mark ZuckerComputational Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Minsoo KimComputational Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Paul RussoDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Jonathan ColemanDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Chung-Han LeeGenitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Maria I CarloGenitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Ying-Bei ChenDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
A Ari HakimiDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Ritesh R KotechaGenitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Ed ReznikComputational Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Memorial Sloan Kettering Cancer Center · USUniversity of Birmingham · GB

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Renal medullary carcinoma (RMC) is a highly aggressive disease associated with sickle hemoglobinopathies and universal loss of the tumor suppressor gene

Indexed as

CD70ferroptosisrenal cell carcinoma (RCC)single-cell RNASMARCB1

Identifiers

PMID35837094
PMCPMC9275834
OpenAlexW4283694851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.