Evidence map›Paper›PMID 35836805›Full record

ArticleTheranostics2022

A theranostic 3D ultrasound imaging system for high resolution image-guided therapy.

Hanna Bendjador, Josquin Foiret, Robert Wodnicki, Douglas N Stephens, Zoe Krut, Eun-Yeong Park, Zulma Gazit, Dan Gazit, Gadi Pelled, Katherine W Ferrara

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hanna BendjadorStanford University, Stanford CA, USA.
Josquin FoiretStanford University, Stanford CA, USA.
Robert WodnickiUniversity of Southern California, Los Angeles CA, USA.
Douglas N StephensUniversity of California, Davis CA USA.
Zoe KrutCedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Eun-Yeong ParkStanford University, Stanford CA, USA.
Zulma GazitCedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Dan GazitCedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Gadi PelledCedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Katherine W FerraraStanford University, Stanford CA, USA.
Cedars-Sinai Medical Center · USStanford University · USUniversity of Southern California · US

Funding

Specific and high-resolution ultrasound cancer imagingR01CA112356 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI FERRARA, KATHERINE W, FOIRET, JOSQUIN · 2005 to 2022
$6.1M
Large aperture and wideband modular ultrasound arrays for the diagnosis of liver cancerR01CA211602 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FERRARA, KATHERINE W, TRAHEY, GREGG E. · 2017 to 2021
$3.3M
Quantitative volumetric ultrasonic and photoacoustic tomographyR01CA258807 · NCI · STANFORD UNIVERSITY · PI Katherine W Ferrara, Steven Poplack · 2022 to 2026
$3.2M
High Resolution Ultrasound in Interventional RadiologyR01CA271309 · NCI · STANFORD UNIVERSITY · PI Katherine W Ferrara, Qifa Zhou · 2022 to 2026
$3.1M
HIFU-immunotherapy in pancreatic cancerR01CA253316 · NCI · STANFORD UNIVERSITY · PI FERRARA, KATHERINE W · 2020 to 2024
$3.1M
Ultrasound-guided DNA delivery for regenerative medicineR01EB026094 · NIBIB · CEDARS-SINAI MEDICAL CENTER · PI GAZIT, DAN · 2018 to 2021
$2.8M
Optimized ultrasound-enhanced immunotherapyR01CA199658 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FERRARA, KATHERINE W · 2015 to 2019
$2.5M
NCI NIH HHS R01 CA112356NCI NIH HHS R01 CA199658NCI NIH HHS R01 CA211602NCI NIH HHS R01 CA253316NCI NIH HHS R01 CA258807NCI NIH HHS R01 CA271309NIBIB NIH HHS R01 EB026094
6 · The paper itself

Abstract

Microbubble contrast agents are a diagnostic tool with broad clinical impact and an increasing number of indications. Many therapeutic applications have also been identified. Yet, technologies for ultrasound guidance of microbubble-mediated therapy are limited. In particular, arrays that are capable of implementing and imaging microbubble-based therapy in three dimensions in real-time are lacking. We propose a system to perform and monitor microbubble-based therapy, capable of volumetric imaging over a large field-of-view. To propel the promise of the theranostic treatment strategies forward, we have designed and tested a unique array and system for 3D ultrasound guidance of microbubble-based therapeutic protocols based on the frequency, temporal and spatial requirements.

Indexed as

Precision MedicineTransducersMicrobubblesPhantoms, ImagingUltrasonographyarray designCPS imagingimage-guided therapymicrobubble imagingVolumetric ultrasound imaging

Identifiers

PMID35836805
PMCPMC9274734
OpenAlexW4285196925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.