Evidence map›Paper›PMID 35836605›Full record

ArticleFrontiers in surgery2022

Case Report: Post-Partum SARS-CoV-2 Infection After the First French Uterus Transplantation.

Jean Marc Ayoubi, Marie Carbonnel, Niclas Kvarnström, Aurelie Revaux, Marine Poulain, Sarah Vanlieferinghen, Yves Coatantiec, Mathilde Le Marchand, Morgan Tourne, Paul Pirtea and 5 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Risks of uterus transplantation: a scoping review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Jean Marc AyoubiDepartment of Obstetrics Gynecology and Reproductive Medicine, Foch Hospital - Paris Ouest Medicine University (UVSQ), Suresnes, France.
Marie CarbonnelDepartment of Obstetrics Gynecology and Reproductive Medicine, Foch Hospital - Paris Ouest Medicine University (UVSQ), Suresnes, France.
Niclas KvarnströmDepartment of Transplantation, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Aurelie RevauxDepartment of Obstetrics Gynecology and Reproductive Medicine, Foch Hospital - Paris Ouest Medicine University (UVSQ), Suresnes, France.
Marine PoulainDepartment of Obstetrics Gynecology and Reproductive Medicine, Foch Hospital - Paris Ouest Medicine University (UVSQ), Suresnes, France.
Sarah VanlieferinghenDepartment of Obstetrics Gynecology and Reproductive Medicine, Foch Hospital - Paris Ouest Medicine University (UVSQ), Suresnes, France.
Yves CoatantiecNeonatal Care Unit, Foch Hospital, Suresnes, France.
Mathilde Le MarchandDepartment of Clinical Research, Foch Hospital, Suresnes, France.
Morgan TourneDepartment of Pathology, Hospital - Paris Ouest Medicine University (UVSQ), Suresnes, France.
Paul PirteaDepartment of Obstetrics Gynecology and Reproductive Medicine, Foch Hospital - Paris Ouest Medicine University (UVSQ), Suresnes, France.
Renaud SnanoudjDepartment of Nephrology and Transplantation, Bicêtre Hospital, Le Kremlin-Bicêtre, France.
Morgan Le GuenDepartment of Anesthesiology, Foch Hospital - Paris Ouest Medicine University (UVSQ), Suresnes, France.
Pernilla Dahm-KählerDepartment of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Catherine RacowskyDepartment of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Boston, MA, USA.
Mats BrännströmNeonatal Care Unit, Foch Hospital, Suresnes, France.
Hôpital Foch · FRUniversité de Versailles Saint-Quentin-en-Yvelines · FRUniversity of Gothenburg · SEBicêtre Hospital · FRBrigham and Women's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Absolute uterus factor infertility, whether congenital or acquired, renders the woman unable to carry a child. Although uterus transplantation (UTx) is being increasingly performed as a non-vital procedure to address this unfortunate condition, the immunosuppression required presents risks that are further compounded by pregnancy and during the puerperium period. These vulnerabilities require avoidance of SARS-CoV-2 infection in pregnant UTx recipients especially during the third trimester, as accumulating evidence reveals increased risks of morbidity and mortality. Here we describe a successful UTx case with delivery of a healthy child, but in which both mother and neonate developed asymptomatic SARS-CoV-2 infection seven days after RNA vaccination, on day 35 post-partum. Although the patient was successfully treated with a combination therapy comprised of two monoclonal antibodies, this case highlights the challenges associated with performing UTx in the era of Covid-19. More broadly, the risks of performing non-vital organ transplantation during a pandemic should be discussed among team members and prospective patients, weighing the risks against the benefits in improving the quality of life, which were considerable for our patient who achieved motherhood with the birth of a healthy child.

Indexed as

uterus transplantation, immunotherapy, COVID-19, SARS-CoV-2, case report

Identifiers

PMID35836605
PMCPMC9273879
OpenAlexW4283656875

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.