Evidence map›Paper›PMID 35836598›Full record

ReviewFrontiers in surgery2022

The Use of Indocyanine Green (ICG) and Near-Infrared (NIR) Fluorescence-Guided Imaging in Gastric Cancer Surgery: A Narrative Review.

Francesco Belia, Alberto Biondi, Annamaria Agnes, Pietro Santocchi, Antonio Laurino, Laura Lorenzon, Roberto Pezzuto, Flavio Tirelli, Lorenzo Ferri, Domenico D'Ugo and 1 more

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07295002 (COmpletion Sentinel Node Resection With or Without Minimally invAsive and Endoscopic Cooperative Surgery Following noncuRative Endoscopic Submucosal Dissection for Early Gastric Cancer), which is not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07295002 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

COmpletion Sentinel Node Resection With or Without Minimally invAsive and Endoscopic Cooperative Surgery Following noncuRative Endoscopic Submucosal Dissection for Early Gastric Cancer

TypeinterventionalSponsorRegion StockholmRan2026 to 2029Enrolled10ConditionsEarly Gastric CancerArmsICG-guided lymphadenectomy, Laparoscopic and endoscopic cooperative surgery (LECS)
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Fluorescence-guided lymphadenectomy in gastric cancer surgery: a novel intraoperative indocyanine green injection.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2026
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  12. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesco BeliaUniversità Cattolica del Sacro Cuore, Rome, Italy.
Alberto BiondiUniversità Cattolica del Sacro Cuore, Rome, Italy.
Annamaria AgnesUniversità Cattolica del Sacro Cuore, Rome, Italy.
Pietro SantocchiUniversità Cattolica del Sacro Cuore, Rome, Italy.
Antonio LaurinoUniversità Cattolica del Sacro Cuore, Rome, Italy.
Laura LorenzonUniversità Cattolica del Sacro Cuore, Rome, Italy.
Roberto PezzutoDipartimento Di Scienze Mediche E Chirurgiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Flavio TirelliUniversità Cattolica del Sacro Cuore, Rome, Italy.
Lorenzo FerriUniversità Cattolica del Sacro Cuore, Rome, Italy.
Domenico D'UgoUniversità Cattolica del Sacro Cuore, Rome, Italy.
Roberto PersianiUniversità Cattolica del Sacro Cuore, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Near-infrared fluorescence imaging with indocyanine green is an emerging technology gaining clinical relevance in the field of oncosurgery. In recent decades, it has also been applied in gastric cancer surgery, spreading among surgeons thanks to the diffusion of minimally invasive approaches and the related development of new optic tools. Its most relevant uses in gastric cancer surgery are sentinel node navigation surgery, lymph node mapping during lymphadenectomy, assessment of vascular anatomy, and assessment of anastomotic perfusion. There is still debate regarding the most effective application, but with relatively no collateral effects and without compromising the operative time, indocyanine green fluorescence imaging carved out a role for itself in gastric resections. This review aims to summarize the current indications and evidence for the use of this tool, including the relevant practical details such as dosages and times of administration.

Indexed as

gastric cancerICGindocyanine Greennear-infrarednear-infrared fluorescence imagingnir

Identifiers

PMID35836598
PMCPMC9273882

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.