Evidence map›Paper›PMID 35836116›Full record

Trial reportBMC anesthesiology2022

The quality of recovery after erector spinae plane block in patients undergoing breast surgery: a randomized controlled trial.

Marcin Wiech, Paweł Piwowarczyk, Marcin Mieszkowski, Bułat Tuyakov, Karolina Pituch-Sala, Tomasz Czarnik, Andrzej Kurylcio, Mirosław Czuczwar, Michał Borys

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04726878 (Effectiveness of the Erector Spinae Plane Block in Patients Undergoing Breast Surgery Due to Cancer), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04726878 phase4completednot on this map

Effectiveness of the Erector Spinae Plane Block in Patients Undergoing Breast Surgery Due to Cancer

TypeinterventionalSponsorMedical University of LublinRan2021 to 2021Enrolled75ConditionsBreast Cancer, Pain, Acute, Anesthesia, LocalArmsErector spinae plane block, Sham block, General anesthesia, Patient-controlled analgesia, Oxycodone
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. The Utility of Erector Spinae Plane Blocks in Breast Surgery: A Practical Review.Plastic and reconstructive surgery. Global open · 2025
    Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Marcin WiechSecond Department of Anesthesiology and Intensive Care Medicine, Medical University of Lublin, ul. Staszica 16, 20-081, Lublin, Poland.
Paweł PiwowarczykSecond Department of Anesthesiology and Intensive Care Medicine, Medical University of Lublin, ul. Staszica 16, 20-081, Lublin, Poland.
Marcin MieszkowskiDepartment of Anesthesiology and Intensive Care, Regional Specialist Teaching Hospital, Olsztyn, Poland.
Bułat TuyakovDepartment of Anesthesiology and Intensive Care, Regional Specialist Teaching Hospital, Olsztyn, Poland.
Karolina Pituch-SalaSecond Department of Anesthesiology and Intensive Care Medicine, Medical University of Lublin, ul. Staszica 16, 20-081, Lublin, Poland.
Tomasz CzarnikDepartment of Anesthesiology, Intensive Care and Regional ECMO Center, Institute of Medical Sciences, Opole University, Opole, Poland.
Andrzej KurylcioDepartment of Surgical Oncology, Medical University of Lublin, ul. Radziwiłłowska 13, 20-080, Lublin, Poland.
Mirosław CzuczwarSecond Department of Anesthesiology and Intensive Care Medicine, Medical University of Lublin, ul. Staszica 16, 20-081, Lublin, Poland.
Michał BorysSecond Department of Anesthesiology and Intensive Care Medicine, Medical University of Lublin, ul. Staszica 16, 20-081, Lublin, Poland. michalborys1@gmail.com.
Medical University of Lublin · PLUniversity of Warmia and Mazury in Olsztyn · PLUniversity of Opole · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe erector spinae plane (ESP) block has recently been shown to effectively alleviate postoperative pain and reduce opioid consumption in breast surgery patients. However, data are still limited concerning the quality of recovery in patients following this procedure.

methodsThis study was a randomized controlled trial (RCT) performed in a university hospital. We randomly allocated patients to one of three groups: ESP, SHAM, and control (CON). Procedures in the ESP and SHAM blocks were performed ipsilaterally with 0.375% ropivacaine or 0.9% saline (0.4 mL/kg). Our primary outcome was the assessment of the patient's improvement with quality-of-recovery 40 (QoR-40) a day after surgery. Other outcome assessments included postoperative pain evaluation on the visual analog scale (VAS), 24-hour opioid consumption with patient-controlled analgesia (PCA), time to the first opioid demand, and global satisfaction with perioperative treatment.

resultsOverall, patients in the ESP group had improved QoR-40 compared to the CON group, 186 [177-193] vs. 175 [165-183] (medians and interquartile ranges). Pain severity was significantly higher in the CON group compared to the ESP group at hours 2 (38 [23-53] vs. 20 [7-32]) and 4 (30 [18-51] vs. 19 [7-25]). Moreover, we observed lower oxycodone consumption after 24 hours with the PCA pump between the ESP (4 [2-8] mg) and the CON (9.5 [5-19]) groups. Patients in the CON group used PCA sooner than those in the ESP group. Participants in the ESP group were more satisfied with treatment than those in the CON group. We found no statistical difference between SHAM and the other groups.

conclusionsCompared to the CON group, the ESP block improved the quality of recovery, alleviated pain intensity, and lowered opioid consumption in patients undergoing breast surgery. However, we did not observe this superiority in comparison with the SHAM group.

trial registrationNCT04726878 .

Indexed as

Breast NeoplasmsNerve BlockAnalgesics, OpioidAnesthetics, LocalFemaleHumansPostoperative PainUltrasonography, InterventionalAnalgesics, OpioidAnesthetics, LocalBreast surgeryErector spinae plane blockPatient-controlled analgesiaQuality of recoveryVisual analog scale

Identifiers

PMID35836116
PMCPMC9281119
OpenAlexW4285387758

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.