ArticlePharmaceutical research2022
Improved Pharmaceutical Properties of Honokiol via Salification with Meglumine: an Exception to Oft-quoted ∆pK
Article in Pharmaceutical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 11 citations in OpenAlex.
- Solubility, Release Behavior and Membrane Permeability of a Ibuprofen Hydrogel Co-Assembled with N-Methyl-D-Glucosamine.Gels (Basel, Switzerland) · 2026Article
- Formation and Release Enhancement of a Novel Small-Molecule Hydrogel Containing Sulindac and Meglumine.Gels (Basel, Switzerland) · 2026Article
- Structural and Spectroscopic Properties of Magnolol and Honokiol-Experimental and Theoretical Studies.International journal of molecular sciences · 2025Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Honokiol (HK), a BCS class II drug with a wide range of pharmacological activities, has poor solubility and low oral bioavailability, severely limiting its clinical application. In the current study, incorporating a water-soluble meglumine (MEG) into the crystal lattice of HK molecule was performed to improve its physicochemical properties. The binary mixture of HK and MEG was obtained by anti-solvent method and characterized by TGA, DSC, FTIR, and PXRD. The SCXRD analysis showed that two HK
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Registered trials
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