Trial reportScientific reports2022
A randomised pilot trial of virtual reality-based relaxation for enhancement of perioperative well-being, mood and quality of life.
Trial report in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Effects of Immersive Virtual Reality Interventions on Symptom Management in Patients With Gastrointestinal Cancer: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- OncoVR - Virtual Reality in Oncology for Patient-centered Care: A Systematic Review and Meta-Analysis.Current oncology reports · 2026Pooled it
- Virtual reality for cancer symptom management: a systematic review of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Integrating Immersive Virtual Reality With Savoring to Promote the Well-Being of Patients With Chronic Respiratory Diseases: Pilot Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- Effects of Virtual Reality on Pain, Stress, and Affect in an Outpatient Chemotherapy Infusion Clinic: A Randomized Controlled Trial.Clinical journal of oncology nursing · 2025Trial
- A scoping review of virtual reality technology utilization in patients with colorectal cancer.BMC nursing · 2026Article
- Evaluation of virtual reality-based meditation as a tool to mitigate stress among parents and providers in the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Virtual reality-based mindfulness applications: a commercial health app review.BMJ health & care informatics · 2026Review
- Extended reality in supporting cancer patients and survivors: A systematic review on the benefits and challenges across the cancer care continuum.Future healthcare journal · 2026Review
- Virtual reality in perioperative medicine: An evidence-based systematic review and meta-analysis.Indian journal of anaesthesia · 2026Article
- Technology-Enabled (P)rehabilitation for Patients Undergoing Cancer Surgery: A Systematic Review and Meta-Analysis.Cancers · 2026Review
- The effects of VR/AR/MR-based interventions on symptom management among adult cancer survivors receiving active treatments: a systematic review and meta-analysis.Journal of cancer survivorship : research and practice · 2025Review
- Effects and Acceptability of a 1-Week Home-Based Virtual Reality Training for Supporting the Management of Stress and Anxiety: Randomized Pilot Trial.JMIR serious games · 2025Article
- Feasibility, Subjective Effectiveness, and Acceptance of Short Virtual Reality Relaxation Breaks for Immediate Perceived Stress Reduction in Emergency Physicians: Single-Arm Pre-Post Intervention Study.JMIR XR and spatial computing · 2025Article
- A Systematic Review of Virtual Reality's Impact on Anxiety During Palliative Care.Healthcare (Basel, Switzerland) · 2024Review
- A nature-immersive virtual reality intervention to support hospice family caregivers: Qualitative findings from a pilot study.Asia-Pacific journal of oncology nursing · 2024Article
- Article
- Virtual stressors with real impact: what virtual reality-based biobehavioral research can teach us about typical and atypical stress responsivity.Translational psychiatry · 2024Review
- XR and mental wellbeing: state of the art and future research directions for the Metaverse.Frontiers in psychology · 2024Review
- An Intervention on Anxiety Symptoms in Moderate Alzheimer's Disease through Virtual Reality: A Feasibility Study and Lessons Learned.International journal of environmental research and public health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A cancer diagnosis and subsequent treatment can trigger distress, negatively impact coping resources, and affect well-being as well as quality of life. The aim of this pilot study was to investigate feasibility and clinical effects of a VR intervention on quality of life, well-being and mood in cancer patients undergoing surgery compared to a non-VR intervention and a control group. 54 patients with colorectal cancer or liver metastases from colorectal cancer undergoing elective curatively intended surgery were recruited and randomised to one of two intervention groups or a control group receiving standard treatment. Participants assigned to one of the intervention groups either received a VR-based intervention twice daily or listened to music twice daily. Adherence to the intervention was 64.6% in the music group and 81.6% in the VR group. The VR intervention significantly reduced heart rate (- 1.2 bpm; 95% CI - 2.24 to - 0.22; p = 0.02) and respiratory rate (- 0.7 brpm; 95% CI - 1.08 to - 0.25; p = 0.01). Self-reported overall mood improved in both groups (VR: + 0.79 pts; 95% CI 0.37-1.21; p = 0.001; music: + 0.59 pts; 95% CI 0.22-0.97; p = 0.004). There was no difference in quality of life between the three groups. Both interventions groups reported changes in feelings. Adherence rates favoured the VR intervention over the music group. Observed clinical outcomes showed stronger intragroup effects on mood, feelings, and vital signs in the VR group. The study demonstrated feasibility of a VR intervention in cancer patients undergoing surgery and should encourage further research investigating the potential of VR interventions to positively influence well-being and mood in cancer patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.