Evidence map›Paper›PMID 35835916›Full record

ArticleScientific reports2022

Electrochemical detection of uric acid in undiluted human saliva using uricase paper integrated electrodes.

Seong Hyun Han, You-Jung Ha, Eun Ha Kang, Kichul Shin, Yun Jong Lee, Gi-Ja Lee

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Seong Hyun HanDepartment of Medical Engineering, Kyung Hee University, Graduate School, Seoul, 02447, Republic of Korea.
You-Jung HaDivision of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, 13620, Republic of Korea.
Eun Ha KangDivision of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, 13620, Republic of Korea.
Kichul ShinDivision of Rheumatology, Seoul Metropolitan Government-Seoul National University Boramae Medical Centre, Seoul, 07061, Republic of Korea.
Yun Jong LeeDivision of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, 13620, Republic of Korea. yn35@snu.ac.kr.
Gi-Ja LeeDepartment of Medical Engineering, Kyung Hee University, Graduate School, Seoul, 02447, Republic of Korea. gjlee@khu.ac.kr.
Seoul National University Bundang Hospital · KRKyung Hee University · KRKyung Hee University Medical Center · KRSeoul Metropolitan Government · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we introduce a uricase-immobilized paper (UOx--paper) integrated electrochemical sensor for detection of uric acid (UA) in saliva. The UOx was immobilized on the detection zone in the wax-patterned paper substrate. This UOx-paper was integrated with a Prussian blue--modified, screen-printed carbon electrode after electropolymerization of o-phenylenediamine to construct an electrochemical cell for small-volume (20 μL) of samples. First, we optimized the fabrication conditions of UOx-paper. Next, the amperometric response of the UOx-paper-based electrochemical UA sensor was analyzed using a known concentration of UA standard solution in artificial saliva at an applied potential of - 0.1 V (versus Ag pseudo-reference electrode). The UOx--paper based electrochemical UA sensor showed a sensitivity of 4.9 μA·mM

Indexed as

Biosensing TechniquesUrate OxidaseElectrochemical TechniquesElectrodesHumansReproducibility of ResultsSalivaUric AcidUrate OxidaseUric Acid

Identifiers

PMID35835916
PMCPMC9283454
OpenAlexW4285495066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.