Evidence map›Paper›PMID 35835801›Full record

ArticleScientific reports2022

High B-value diffusion tensor imaging for early detection of hippocampal microstructural alteration in a mouse model of multiple sclerosis.

Amandine Crombé, Renaud Nicolas, Nathalie Richard, Thomas Tourdias, Bassem Hiba

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Amandine Crombé *INSERM, U1215, Neurocentre Magendie, 33000, Bordeaux, France.
Renaud Nicolas *Aquitaine Institute for Cognitive and Integrative Neuroscience (INCIA), UMR 5287, CNRS, Université de Bordeaux, Bordeaux, France.
Nathalie RichardInstitute of Cognitive Neuroscience Marc Jeannerod, CNRS/UMR 5229, 69500, Bron, France.
Thomas TourdiasINSERM, U1215, Neurocentre Magendie, 33000, Bordeaux, France.
Bassem HibaInstitute of Cognitive Neuroscience Marc Jeannerod, CNRS/UMR 5229, 69500, Bron, France. bassem.hiba@cnrs.fr.
Centre National de la Recherche Scientifique · FRGroupe de Recherche en Agriculture Biologique · FRInstitut des Sciences Cognitives · FRNeurocentre Magendie · FRUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have highlighted the value of diffusion tensor imaging (DTI) with strong diffusion weighting to reveal white matter microstructural lesions, but data in gray matter (GM) remains scarce. Herein, the effects of b-values combined with different numbers of diffusion-encoding directions (NDIRs) on DTI metrics to capture the normal hippocampal microstructure and its early alterations were investigated in a mouse model of multiple sclerosis (experimental autoimmune encephalomyelitis [EAE]). Two initial DTI datasets (B2700-43Dir acquired with b = 2700 s.mm

Indexed as

Encephalomyelitis, Autoimmune, ExperimentalMultiple SclerosisWhite MatterAnimalsDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingDisease Models, AnimalGray MatterHippocampusMice

Identifiers

PMID35835801
PMCPMC9283448
OpenAlexW4285390377

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.