Evidence map›Paper›PMID 35835577›Full record

ArticleInternational journal of spine surgery2022

Is Sarcopenia a Risk Factor for Postoperative Surgical Site Infection After Posterior Lumbar Spinal Fusion?

Francesca Barile, Alberto Ruffilli, Michele Fiore, Marco Manzetti, Giuseppe Geraci, Giovanni Viroli, Cesare Faldini

Abstract read
In one paragraph

Article in International journal of spine surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Development of a risk scoring system for surgical site infection after lumbar surgery using Dixon MRI and clinical parameters.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  6. Article
  7. Article
  8. The cross-sectional area of gluteal muscle on multiaxial CT scan as a predictor for diagnosing sarcopenia in patients with degenerative lumbar disease.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francesca BarileFirst Orthopaedic and Traumatologic Clinic - IRCCS Istituto Ortopedico Rizzoli (IOR), Bologna, Italy.
Alberto RuffilliFirst Orthopaedic and Traumatologic Clinic - IRCCS Istituto Ortopedico Rizzoli (IOR), Bologna, Italy.
Michele FioreFirst Orthopaedic and Traumatologic Clinic - IRCCS Istituto Ortopedico Rizzoli (IOR), Bologna, Italy michele.fiore@ior.it.
Marco ManzettiFirst Orthopaedic and Traumatologic Clinic - IRCCS Istituto Ortopedico Rizzoli (IOR), Bologna, Italy.
Giuseppe GeraciFirst Orthopaedic and Traumatologic Clinic - IRCCS Istituto Ortopedico Rizzoli (IOR), Bologna, Italy.
Giovanni ViroliFirst Orthopaedic and Traumatologic Clinic - IRCCS Istituto Ortopedico Rizzoli (IOR), Bologna, Italy.
Cesare FaldiniFirst Orthopaedic and Traumatologic Clinic - IRCCS Istituto Ortopedico Rizzoli (IOR), Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis retrospective observational study aimed to evaluate the impact of sarcopenia on surgical site infection (SSI) risk in patients who undergo posterior lumbar fusion. While many studies have investigated the impact of sarcopenia on postoperative morbidity both in general and orthopedic surgery, none of them examined the risk of postoperative infection after lumbar spine surgery in sarcopenic vs nonsarcopenic patients.

methodsConsecutive 55- to 75-year-old patients who underwent short posterior lumbar fusion for degenerative pathology between 2004 and 2019 were included. Charts were reviewed, and the psoas:lumbar vertebral index (PLVI) was used as a measure of central sarcopenia. Patients were stratified according to low vs high PLVI and then according to postoperative infection status. SSI was assessed as an outcome. A statistical analysis was performed to identify risk factors for infection.

resultsA total of 304 patients were included; 24 (7.9%) developed postoperative SSI. The average follow-up was 26.2 months. The sarcopenic group was found to not have a higher likelihood of experiencing postoperative SSI (

conclusionsLow PLVI was not associated with postoperative SSI in this study. This finding is in contrast with the findings of other authors who found sarcopenia to be a risk factor for postoperative complications. However, these studies did not consider SSI as the only primary endpoint, and patients were not stratified by indication (degeneration, infection, tumor, and trauma) or surgical procedure. CLINICAL RELEVANCE: Low PLVI was not associated with postoperative SSI in patients who undergo short posterior lumbar fusion for degenerative pathology. LEVEL OF EVIDENCE: 3:

Indexed as

infection risklumbar degenerative diseaselumbar fusionsarcopeniasurgical site infection

Identifiers

PMID35835577
PMCPMC9421281

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.