Evidence map›Paper›PMID 35835567›Full record

ArticleInternational journal of spine surgery2022

Perioperative Chanage in Cervical Lordosis and Health-Related Quality-of-Life Outcomes.

Jose A Canseco, Brian A Karamian, Parthik D Patel, Michael Markowitz, Joseph K Lee, Mark F Kurd, D Greg Anderson, Jeffrey A Rihn, Alan S Hilibrand, Christopher K Kepler and 2 more

Abstract read
In one paragraph

Article in International journal of spine surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jose A CansecoRothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.
Brian A KaramianRothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA brian.karamian@rothmanortho.com.
Parthik D PatelRothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.
Michael MarkowitzRothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.
Joseph K LeeRothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.
Mark F KurdRothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.
D Greg AndersonRothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.
Jeffrey A RihnRothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.
Alan S HilibrandRothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.
Christopher K KeplerRothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.
Alexander R VaccaroRothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.
Gregory D SchroederRothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgeons have scrutinized spinal alignment and its impact on improving clinical outcomes following anterior cervical discectomy and fusion (ACDF). The primary analysis of this study examines the relationship between change in perioperative cervical lordosis (CL) and health-related quality-of-life (HRQOL) outcomes after ACDF. Secondary analysis evaluates the effects of fusion construct length on outcomes in patients grouped by preoperative cervical alignment.

methodsA retrospective cohort study was performed on an institutional database including patients who underwent 1- to 3-level ACDF. C2-C7 CL was measured preoperatively and at final follow-up. For primary analysis, patients were classified based on their perioperative cervical lordotic correction: (1) kyphotic, (2) maintained, and (3) restored. For secondary analysis, patients were categorized based on their preoperative C2-C7 CL: (1) kyphotic, (2) neutral, and (3) lordotic. Demographics and perioperative change in patient-reported outcome measures were compared between groups.

resultsA total of 308 patients were included. A significant difference was noted among maintained, restored, and kyphotic groups in terms of delta physical compositeshort form-12 score (ΔPCS-12) (9.0 vs 10.3 vs 1.5;

conclusionsSignificantly greater PCS-12 and VAS arm improvement were seen in patients whose cervical sagittal alignment was restored to neutral/lordotic compared with those who remained kyphotic. Multivariate analysis demonstrated no association between construct length and perioperative outcomes. CLINICAL RELEVANCE: The results of this study highlight the importance of sagittal alignment and restoration of CL after short-segment ACDF. Irrespective of preoperative sagittal alignment, the length of ACDF fusion construct does not have a significant impact on clinical outcomes. LEVEL OF EVIDENCE: 3:

Indexed as

alignment, HRQOLanterior cervical discectomy and fusion (ACDF)cervical lordosisconstruct lengthkyphosispatient-reported clinical outcomes (PROMs)

Identifiers

PMID35835567
PMCPMC9807057

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.