Evidence map›Paper›PMID 35834958›Full record

ArticleCell host & microbe2022

Gut microbiota gestalt.

Jonathan Melamed, Gabrielle LeBlanc, Michael G Constantinides

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell host & microbe, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. In Vivo Evaluation of the Effect ofInternational journal of molecular sciences · 2026
    Article
  2. Progress on the mechanism of intestinal microbiota against colorectal cancer.Frontiers in cellular and infection microbiology · 2025
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jonathan MelamedDepartment of Immunology & Microbiology, Scripps Research, La Jolla, CA 92037, USA.
Gabrielle LeBlancDepartment of Immunology & Microbiology, Scripps Research, La Jolla, CA 92037, USA.
Michael G ConstantinidesDepartment of Immunology & Microbiology, Scripps Research, La Jolla, CA 92037, USA. Electronic address: constantinides@scripps.edu.

Funding

Modulation of in vivo MAIT cell responses with diverse MR1 ligandsR21AI171697 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI CONSTANTINIDES, MICHAEL GEORGE · 2022 to 2023
$488k
Crosstalk between MAIT cells and the microbiotaK22AI146217 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI CONSTANTINIDES, MICHAEL GEORGE · 2021 to 2022
$270k
NIAID NIH HHS K22 AI146217NIAID NIH HHS R21 AI171697
6 · The paper itself

Abstract

The pathogenicity of disease-associated microbes varies widely between individuals. In this issue of Cell Host & Microbe, Rice et al. demonstrate that interactions between intestinal commensals reciprocally modulate the host immune response to each microbe, ameliorating the inflammation caused by one and dampening antibody responses to the other.

Indexed as

Gastrointestinal MicrobiomeHumansInflammationIntestinesSymbiosis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.