Evidence map›Paper›PMID 35834774›Full record

ReviewPhysiological reviews2022

Complex physiology and clinical implications of time-restricted eating.

Max C Petersen, Molly R Gallop, Stephany Flores Ramos, Amir Zarrinpar, Josiane L Broussard, Maria Chondronikola, Amandine Chaix, Samuel Klein

2 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Physiological reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 52 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 5 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06455995 narecruitingnot on this mapstarted 2024, after this paper: background citation

Effect of Time-based Energy Intake Goals on Weight Loss During Obesity Treatment

TypeinterventionalSponsorThe University of Tennessee, KnoxvilleRan2024 to 2028Enrolled174ConditionsObesityArmsDEPTH, DEPTH-Morning, DEPTH-Evening
NCT07262593 naterminatednot on this mapstarted 2024, after this paper: background citation

Family-Based Meal Timing for Cancer Prevention Among Native Hawaiian and Other Pacific Islanders: FAMTIME

TypeinterventionalSponsorUniversity of UtahRan2024 to 2024Enrolled2ConditionsCancer PreventionArmsTime Restricted Eating (TRE), Medically Tailored Meals (MTM)
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 5 syntheses or guidelines pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Understanding Participants' and Health Professionals' Perceptions and Experiences of Time-Restricted Eating: A Systematic Review of Qualitative Evidence.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Elucidation of daily timed-palatable meal-anticipatory activity in the circadian system of mice.American journal of physiology. Gastrointestinal and liver physiology · 2026
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Max C PetersenCenter for Human Nutrition, Washington University School of Medicine, St. Louis, Missouri.ORCID 0000-0001-8646-2377
Molly R GallopDepartment of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah.
Stephany Flores RamosDivision of Gastroenterology, University of California, San Diego, La Jolla, California.
Amir ZarrinparDivision of Gastroenterology, University of California, San Diego, La Jolla, California.
Josiane L BroussardDivision of Endocrinology, Metabolism, and Diabetes, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Maria ChondronikolaDepartments of Nutrition and Radiology, University of California, Davis, California.
Amandine ChaixDepartment of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah.
Samuel KleinCenter for Human Nutrition, Washington University School of Medicine, St. Louis, Missouri.ORCID 0000-0001-7127-1156
University of Utah · USWashington University in St. Louis · USHarokopio University of Athens · GRSan Francisco VA Medical Center · USUniversity of California San Diego · USUniversity of Colorado Anschutz Medical Campus · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Alan Saghatelian · 1985 to 2026
$82.8M
UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
The Southernearch Center for ALPD and CirrhosisP50AA011999 · NIAAA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HIDEKAZU TSUKAMOTO · 1999 to 2026
$45.8M
Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MILES Frome WILKINSON · 2003 to 2026
$40.4M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS · 1995 to 2026
$32.6M
Washington University DDRCC Supplemental Equipment RequestP30DK052574 · NIDDK · WASHINGTON UNIVERSITY · PI Jeffrey Wade Brown · 2000 to 2026
$30.8M
Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GERMAN, MICHAEL S · 2003 to 2019
$21.8M
DIABETES &RELATED METABOLIC DISEASEST32DK007120 · NIDDK · WASHINGTON UNIVERSITY · PI MARCO COLONNA, Maria Sara Remedi · 1986 to 2026
$15.7M
BLRD VA I01 BX005707NCATS NIH HHS UL1 TR001442NCATS NIH HHS UL1 TR001860NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA014195NCI NIH HHS U01 CA265719NHLBI NIH HHS R01 HL148801NIAAA NIH HHS P50 AA011999NIA NIH HHS R01 AG065993NIBIB NIH HHS R01 EB030134NIDDK NIH HHS K08 DK102902NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK048520NIDDK NIH HHS P30 DK052574NIDDK NIH HHS P30 DK056341NIDDK NIH HHS P30 DK063491NIDDK NIH HHS P30 DK063720NIDDK NIH HHS P30 DK098722NIDDK NIH HHS P30 DK120515NIDDK NIH HHS R01 DK115502NIDDK NIH HHS R01 DK125653NIDDK NIH HHS R03 DK114536NIDDK NIH HHS T32 DK007120NIDDK NIH HHS T32 DK110966
6 · The paper itself

Abstract

Time-restricted eating (TRE) is a dietary intervention that limits food consumption to a specific time window each day. The effect of TRE on body weight and physiological functions has been extensively studied in rodent models, which have shown considerable therapeutic effects of TRE and important interactions among time of eating, circadian biology, and metabolic homeostasis. In contrast, it is difficult to make firm conclusions regarding the effect of TRE in people because of the heterogeneity in results, TRE regimens, and study populations. In this review, we

Indexed as

Circadian RhythmFastingBody WeightEatingHumanschrononutritionintermittent fastingnutritionobesitytime-restricted eating

Identifiers

PMID35834774
PMCPMC9423781
OpenAlexW4285388525

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.