Evidence map›Paper›PMID 35834132›Full record

ArticleUpdates in surgery2023

Current molecular biomarkers evaluation in gastric/gastroesophageal junction adenocarcinoma: pathologist does matter.

Gianluca Businello, Valentina Angerilli, Sara Lonardi, Francesca Bergamo, Michele Valmasoni, Fabio Farinati, Edoardo Savarino, Gaya Spolverato, Matteo Fassan

Abstract read
In one paragraph

Article in Updates in surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Heterogeneity of predictive biomarker expression in gastric and esophago-gastric junction carcinoma with peritoneal dissemination.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Article
  5. Review
  6. Concordance of microsatellite instability and mismatch repair status in paired biopsies and surgical specimens of resectable gastroesophageal adenocarcinoma: time for a call to action.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2023
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gianluca Businello *Department of Medicine (DIMED), University of Padua, Padua, Italy.
Valentina Angerilli *Department of Medicine (DIMED), University of Padua, Padua, Italy.
Sara LonardiVeneto Institute of Oncology, Istituto Di Ricovero E Cura a Carattere Scientifico (IRCCS), Padua, Italy.
Francesca BergamoVeneto Institute of Oncology, Istituto Di Ricovero E Cura a Carattere Scientifico (IRCCS), Padua, Italy.
Michele ValmasoniDepartment of Surgery, Oncology and Gastroenterology (DISCOG), University of Padua, Padua, Italy.
Fabio FarinatiDepartment of Surgery, Oncology and Gastroenterology (DISCOG), University of Padua, Padua, Italy.
Edoardo SavarinoDepartment of Surgery, Oncology and Gastroenterology (DISCOG), University of Padua, Padua, Italy.
Gaya SpolveratoDepartment of Surgery, Oncology and Gastroenterology (DISCOG), University of Padua, Padua, Italy.
Matteo FassanDepartment of Medicine (DIMED), University of Padua, Padua, Italy. matteo.fassan@unipd.it.ORCID http://orcid.org/0000-0001-6515-5482

Funding

Associazione Italiana per la Ricerca sul Cancro 22759Regione del Veneto NET-2016-02363853
6 · The paper itself

Abstract

The comprehensive molecular characterization of gastric and gastroesophageal junction adenocarcinomas has led to the improvement of targeted and more effective treatments. As a result, several biomarkers have been introduced into clinical practice and the implementation of innovative diagnostic tools is under study. Such assessments are mainly based on the evaluation of limited biopsy material in clinical practice. In this setting, the pathologist represents a key player in the selection of patients facilitating precision medicine approaches.

Indexed as

AdenocarcinomaEsophageal NeoplasmsStomach NeoplasmsBiomarkersBiomarkers, TumorEsophagogastric JunctionHumansPathologistsBiomarkersBiomarkers, TumorBiomarkersGastric adenocarcinomaGastroesophageal junction adenocarcinomaImmunohistochemistry

Identifiers

PMID35834132
PMCPMC9852175

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.