ArticleIndian journal of pediatrics2023
Evaluation of Changes in Quadriceps Femoris Muscle in Critically III Children Using Ultrasonography.
Article in Indian journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.
- Point-of-care ultrasound in nutrition assessment and enteral nutrition management of critically ill children: a scoping review.Frontiers in nutrition · 2026Pooled it
- The relationship between muscle mass changes and protein or energy intake in critically ill children: A systematic review and meta-analysis.JPEN. Journal of parenteral and enteral nutrition · 2025Pooled it
- Prevalence and magnitude of muscle loss in the pediatric intensive care unit assessed by ultrasound: a systematic review and meta-analysis.Jornal de pediatria · 2026Review
- Point of care ultrasonography of quadriceps femoris muscle thickness for assessing nutritional status in critically ill children.Scientific reports · 2025Article
- Prevalence of muscle atrophy in pediatric patients during ICU hospitalization.European journal of pediatrics · 2024Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo measure changes in muscle thickness and echogenicity, reflecting muscle bulk and quality, respectively, of quadriceps femoris (QF), in critically ill children.
methodsThis study was done on 58 children aged 1-18 y requiring mechanical ventilation, admitted in a pediatric intensive care unit (PICU) of a tertiary care hospital from January 2018 to June 2019. QF thickness was measured twice in longitudinal plane and twice in transverse plane, and an average of these four measurements was used. Muscle quality was assessed using ImageJ software to determine the mean echogenicity, and was calculated separately for vastus intermedius and rectus femoris. These observations were repeated on day 3 and day 7 of the ICU stay.
resultsThe median muscle thickness of QF was 1.58 cm, and vastus intermedius and rectus femoris echogenicity was 35.5 and 25.88 units, respectively in the present cohort, with median age of 6 y. Only 36 of the 58 patients underwent day 7 ultrasonography, as the remainder were either extubated or died. There was no significant change in the muscle thickness over 7 d. Rectus femoris echogenicity increased significantly over 7 d by 16.1% (p = 0.03). Baseline vastus intermedius echogenicity was significantly higher in patients who subsequently died during the course of their illness (p = 0.026).
conclusionThere was a significant change in rectus femoris echogenicity, but not in QF thickness. Echogenicity rather than muscle thickness may be a more sensitive marker for changes in muscle properties.
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Registered trials
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