Evidence map›Paper›PMID 35834111›Full record

ArticleLa Radiologia medica2022

Performance of CT radiomics in predicting the overall survival of patients with stage III clear cell renal carcinoma after radical nephrectomy.

Dong Han, Nan Yu, Yong Yu, Taiping He, Xiaoyi Duan

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Article in La Radiologia medica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  18. Peritoneal Carcinosis: What the Radiologist Needs to Know.Diagnostics (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dong HanDepartment of Medical Image, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277 West Yanta Road, Xi'an, 710061, Shaanxi, China.
Nan YuDepartment of Radiology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.
Yong YuDepartment of Radiology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.
Taiping HeDepartment of Radiology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.
Xiaoyi DuanDepartment of Medical Image, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277 West Yanta Road, Xi'an, 710061, Shaanxi, China. jdduanxiaoyi@sina.com.ORCID http://orcid.org/0000-0003-0337-2590

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the performance of CT radiomics in predicting the overall survival (OS) of patients with stage III clear cell renal carcinoma (ccRCC) after radical nephrectomy. MATERIALS AND

methodsThe 132 patients with stage III ccRCC undergoing radical nephrectomy were collected, and the patients were divided into training set (n = 79) and validation set (n = 53). The ccRCC was segmented and 396 radiomics features were extracted. After dimensionality reduction, radiomics score (RS) was obtained. COX regression was used to construct Model 1 (clinical variables + CT findings) and Model 2 (clinical variables + CT findings + RS) in the training set to predict the OS of patients, and then, the performance of the two models in the two data sets was compared.

resultsIn the training set, Akaike information criterion, C-index, and corrected C-index were 295.51, 0.744, and 0.728 for Model 1, and 271.78, 0.805, and 0.799 for Model 2, respectively. In the validation set, the corresponding values were 185.68, 0.701, and 0.699 for Model 1, and 175.99, 0.768, and 0.768 for Model 2. The calibration curves showed that both models had good calibration degrees in the validation set. Compared with Model 1, the continuous net reclassification index and integrated discrimination improvement index of Model 2 in the two data sets were positively improved.

conclusionThe two prediction models showed high performance in the evaluation of OS of stage III ccRCC patients after radical nephrectomy, among which Model 2 based on ISUP grade and RS was more concise and efficient.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsTesticular NeoplasmsHumansMaleNephrectomyRetrospective StudiesTomography, X-Ray ComputedClear cell renal cell carcinomaOverall survivalRadical nephrectomyRadiomics

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.