ArticleWomen's health (London, England)
Premenstrual and menstrual changes reported after COVID-19 vaccination: The EVA project.
Article in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Menstrual disturbance associated with COVID-19 vaccines: A comprehensive systematic review and meta-analysis.PloS one · 2025Pooled it
- Menstrual disorders following COVID-19 vaccination: a review using a systematic search.Frontiers in drug safety and regulation · 2024Pooled it
- Effect of COVID-19 vaccination on the menstrual cycle.Frontiers in medicine · 2022Pooled it
- Physiological Response to the COVID-19 Vaccine: Insights From a Prospective, Randomized, Single-Blinded, Crossover Trial.Journal of medical Internet research · 2024Trial
- Menstrual Disorders Following Covid 19 Vaccination in Women of Reproductive Age and Post-Menopause. A Systematic Review.Health science reports · 2025Review
- Impact of COVID-19 Vaccination on Menstrual Irregularities, Bleeding Patterns, and Cycle Duration: A Systematic Review and Meta-Analysis.Health science reports · 2025Review
- Relation Between COVID-19 Infection and Vaccine and Menstrual Cycle Changes of Portuguese Adolescents in Higher Education.Healthcare (Basel, Switzerland) · 2024Article
- Menopause symptom prevalence in three post-COVID-19 syndrome clinics in England: A cross-sectional analysis.IJID regions · 2024Article
- The prevalence of menstrual changes in COVID-19 vaccinated women: A cross-sectional study.Preventive medicine reports · 2024Article
- The association of COVID-19 vaccination and menstrual health: A period-tracking app-based cohort study.Vaccine: X · 2024Article
- Association between COVID-19 vaccination and menstruation: a state of the science review.BMJ sexual & reproductive health · 2024Review
- The direct effect of SARS-CoV-2 virus vaccination on human ovarian granulosa cells explains menstrual irregularities.NPJ vaccines · 2024Article
- Article
- Messenger RNA Therapy for Female Reproductive Health.Molecular pharmaceutics · 2024Review
- Knowledge, Attitudes, and Practices Two Years after the Start of the COVID-19 Pandemic: A Mixed Methods Study.Journal of nursing management · 2024Article
- Comparison of menstrual cycle irregularities among young women based on coronavirus disease 2019 infection status: a cross-sectional study.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Saudi Women's Perception of the Effect of COVID-19 Infection and Vaccination on Menstrual Cycle Length.Women's health reports (New Rochelle, N.Y.) · 2024Article
- Article
- Article
- The Impact of COVID-19 on Menstrual Cycle in Women.Journal of clinical medicine · 2023Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMenstrual disorders were not reported as a possible secondary effect in any of the clinical trials for the SARS-CoV-2 vaccines.
aimTo describe the prevalence of perceived premenstrual and menstrual changes after COVID-19 vaccine administration.
designCross-sectional study.
methodsA total of 14,153 women (mean age 31.5 ± 9.3 years old) who had received the full course of vaccination at least three months earlier were included in this cross-sectional study. Data including the type of vaccine administered, perceived changes in the amount and duration of menstrual bleeding, presence of clots, cycle length, and premenstrual symptoms were collected through a retrospective online survey from June to September 2021.
resultsOf the women who participated in this study, 3136 reported no menstrual changes and 11,017 (78% of the study sample) reported experiencing menstrual cycle changes after vaccination. In summary, women who reported menstrual changes after vaccination were older (overall
conclusionWomen vaccinated against COVID-19 usually perceive mild menstrual and premenstrual changes. Future studies are warranted to clarify the physiological mechanisms behind these widely reported changes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.