Evidence map›Paper›PMID 35833655›Full record

ArticleAmerican journal of Alzheimer's disease and other dementias

Urinary AD7c-NTP Evaluates Cognition Impairment and Differentially Diagnoses AD and MCI.

Ming-Ran Xu, Rong-Fang Dai, Qing-Qi Wei, Jun Wang, Yue-Ying Feng, Ying Hu

Abstract read
In one paragraph

Article in American journal of Alzheimer's disease and other dementias. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ming-Ran XuDepartment of Neurology, The Huangpu Branch of Shanghai No. 9 People's Hospital, 56695Shanghai Jiao Tong University Medical School, Shanghai, PR China.
Rong-Fang DaiDepartment of Gerontology, Shanghai No. 9 People's Hospital, 56695Shanghai Jiao Tong University Medical School, Shanghai, PR China.
Qing-Qi WeiDepartment of Neurology, The Huangpu Branch of Shanghai No. 9 People's Hospital, 56695Shanghai Jiao Tong University Medical School, Shanghai, PR China.
Jun WangDepartment of Neurology, The Huangpu Branch of Shanghai No. 9 People's Hospital, 56695Shanghai Jiao Tong University Medical School, Shanghai, PR China.
Yue-Ying FengDepartment of Gerontology, Shanghai No. 9 People's Hospital, 56695Shanghai Jiao Tong University Medical School, Shanghai, PR China.
Ying HuDepartment of Neurology, The Huangpu Branch of Shanghai No. 9 People's Hospital, 56695Shanghai Jiao Tong University Medical School, Shanghai, PR China.ORCID 0000-0003-0915-2580

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The AD7c-NTP is a promising biomarker for AD diagnosis. However, the exact urinary AD7c-NTP concentration to differentiate AD from the mild cognitive impairment (MCI) remains inconclusive. We enrolled 98 and 90 clinical defined AD and MCI patients, respectively, and access their cognition impairment with Neuropsychiatric Inventory (NPI) and Mental State Examination (MMSE) along with their urinary AD7c-NTP. We demonstrated that urinary AD7c-NTP level in sequence from high to low was AD, MCI, and healthy groups (

Indexed as

Alzheimer DiseaseCognitive DysfunctionNerve Tissue ProteinsCognitionHumansNeuropsychological TestsAD7c-NTPAD7c-NTP protein, humanNerve Tissue ProteinsAD7c-NTPAlzheimer’s diseasemild cognitive impairmentneuropsychologyurine

Identifiers

PMID35833655
PMCPMC10581138

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.