Evidence map›Paper›PMID 35833108›Full record

ReviewFrontiers in medicine2022

The State of the Art of Radiotherapy for Non-melanoma Skin Cancer: A Review of the Literature.

Sofian Benkhaled, Dirk Van Gestel, Carolina Gomes da Silveira Cauduro, Samuel Palumbo, Veronique Del Marmol, Antoine Desmet

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07347392 (The Role of Radiotherapy for the Management of Non-melanoma Skin Cancer in Denmark), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07347392 enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

The Role of Radiotherapy for the Management of Non-melanoma Skin Cancer in Denmark

Typeobservational_patient_registrySponsorUniversity of AarhusRan2025 to 2029Enrolled2,900ConditionsNon-Melanoma Skin Cancer (NMSC), Basal Cell Carcinoma of Skin, Squamous Cell Carcinoma of the SkinArmsFollow-up visit at least two years after treatment
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Expert opinion: radiotherapy for basal cell carcinoma : Recommendations from the DEGRO Dermatooncology Working Group.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  3. Article
  4. Efficacy and Safety of Epidermal Radionuclide Therapy withJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
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  9. Review
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sofian BenkhaledDepartment of Radiation-Oncology, Institut Jules Bordet-Université Libre de Bruxelles, Brussels, Belgium.
Dirk Van GestelDepartment of Radiation-Oncology, Institut Jules Bordet-Université Libre de Bruxelles, Brussels, Belgium.
Carolina Gomes da Silveira CauduroDepartment of Radiation-Oncology, Institut Jules Bordet-Université Libre de Bruxelles, Brussels, Belgium.
Samuel PalumboDepartment of Radiation-Oncology, Jolimont Hospital, La Louvière, Belgium.
Veronique Del MarmolDepartment of Dermatology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Antoine DesmetDepartment of Radiation-Oncology, Institut Jules Bordet-Université Libre de Bruxelles, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the general aging population and the fashion trend of sun exposure, non-melanoma skin cancer (NMSC) is rising. The management of NMSC is difficult and necessitates a multidisciplinary team (i.e., pathologists, dermatologists, medical oncologists, surgeons, and radiation oncologists). When surgery is not an option or will cause unacceptably functional morbidity, radiation therapy (RT) may be a preferable tissue-preserving option. Whether used alone or in conjunction with other treatments, RT has been shown to be quite effective in terms of cosmetic results and local control. Contact hypofractionated RT, brachytherapy, and electronic brachytherapy are all promising new treatments. However, rigorous, randomized trials are missing, explaining the disparity in dose, fractionation, and technique recommendations. Therefore, it is essential that interdisciplinary teams better understand RT modalities, benefits, and drawbacks. Our review will provide the role and indications for RT in patients with NMSC.

Indexed as

basal cell carcinomabrachytherapynon-melanoma skin cancerradiotherapysquamous cell carcinoma

Identifiers

PMID35833108
PMCPMC9272768

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.