ArticleiScience2022
Lifespan associations of resting-state brain functional networks with ADHD symptoms.
Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 15 citations in OpenAlex.
- Altered intrinsic connectivity in default mode and somatomotor networks in children and adolescents with ADHD: a neuroimaging meta-analysis.European child & adolescent psychiatry · 2026Article
- Segregation and integration of resting-state brain networks in a longitudinal long COVID cohort.iScience · 2025Article
- Dynamic segregation and integration of brain functional networks associated with emotional arousal.iScience · 2023Article
- Opposite effects of positive and negative symptoms on resting-state brain networks in schizophrenia.Communications biology · 2023Article
- Segregation, integration and balance in resting-state brain functional networks associated with bipolar disorder symptoms.Human brain mapping · 2023Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Attention-deficit/hyperactivity disorder (ADHD) is increasingly being diagnosed in both children and adults, but the neural mechanisms that underlie its distinct symptoms and whether children and adults share the same mechanism remain poorly understood. Here, we used a nested-spectral partition approach to study resting-state brain networks of ADHD patients (n = 97) and healthy controls (HCs, n = 97) across the lifespan (7-50 years). Compared to the linear lifespan associations of brain segregation and integration with age in HCs, ADHD patients have a quadratic association in the whole-brain and in most functional systems, whereas the limbic system dominantly affected by ADHD has a linear association. Furthermore, the limbic system better predicts hyperactivity, and the salient attention system better predicts inattention. These predictions are shared in children and adults with ADHD. Our findings reveal a lifespan association of brain networks with ADHD and provide potential shared neural bases of distinct ADHD symptoms in children and adults.
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Registered trials
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