ArticleArchives of medical science : AMS2022
Cutoff points of T1 rho/T2 mapping relaxation times distinguishing early-stage and advanced osteoarthritis.
Article in Archives of medical science : AMS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Quantitative MRI mapping parameters to differentiate HER2-positive and HER2-low breast cancer.Quantitative imaging in medicine and surgery · 2026Article
- Correlation Between T1 Rho Value of Magnetic Resonance and Clinical Characteristics of Patients with Knee Osteoarthritis and Analysis of Related Factors of T1 Rho Value.International journal of general medicine · 2026Article
- MRI-based patient-specific nomogram for diagnostic risk stratification of patients with early knee OA.Rheumatology (Oxford, England) · 2025Article
- Evaluation of Cartilage Degeneration Using MRI T1ρ Mapping after Locomotion Training in Patients with Early Knee Osteoarthritis.Progress in rehabilitation medicine · 2025Article
- Synthetic Knee MRI TBioengineering (Basel, Switzerland) · 2023Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The histopathology grading system is the gold standard post-operative method to evaluate cartilage degeneration in knee osteoarthritis (OA). Magnetic resonance imaging (MRI) T1 rho/T2 mapping imaging can be used for preoperative detection. An association between histopathology and T1 rho/T2 mapping relaxation times was suggested in previous research. However, the cutoff point was not determined among different histopathology grades. Our study aimed to determine the cutoff point of T1 rho/T2 mapping. Material and methods: T1 rho/T2 mapping images were acquired from 80 samples before total knee replacements. Then the histopathology grading system was applied. Results: The mean T1 rho/T2 mapping relaxation times of 80 samples were 39.17 ms and 37.98 ms respectively. Significant differences were found in T1 rho/T2 mapping values between early-stage and advanced OA ( Conclusions: The cutoff point of T1 rho relaxation times, which was suggested as 33 ms, could be used to distinguish early-stage and advanced OA.
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Registered trials
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