Evidence map›Paper›PMID 35832651›Full record

ArticleJournal of immunology research2022

Chinese Herbal Formula Huayu-Qiangshen-Tongbi Decoction Attenuates Rheumatoid Arthritis through Upregulating miR-125b to Suppress NF-

Xiu-Min Chen, Kai-Xin Gao, Xiao-Dong Wu, Huang-Sheng Liang, Ze-Hao Liu, Mao-Jie Wang, Li-Yan Mei, Qing-Chun Huang, Run-Yue Huang

Abstract read
In one paragraph

Article in Journal of immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiu-Min Chen *State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0003-3378-457X
Kai-Xin Gao *Department of Rheumatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0001-5770-4269
Xiao-Dong Wu *Department of Rheumatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0002-8512-7670
Huang-Sheng LiangSecond Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-5133-3708
Ze-Hao LiuSecond Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-3261-3683
Mao-Jie WangDepartment of Rheumatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0003-1417-416X
Li-Yan MeiDepartment of Rheumatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0003-0587-8325
Qing-Chun HuangState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0002-8769-6658
Run-Yue HuangState Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0003-1532-1766

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Huayu-Qiangshen-Tongbi (HQT) decoction, a Chinese medical formula, has been identified to show a potent therapeutic effect on rheumatoid arthritis (RA). However, the specific molecular mechanism of HQT in RA has not been well studied. In the present study, LPS-treated human rheumatoid fibroblast-like synoviocyte (FLS) MH7A cells and collagen-induced arthritis (CIA) mice were utilized as

Indexed as

Arthritis, RheumatoidMicroRNAsSynoviocytesAnimalsCasein Kinase IIChinaFibroblastsHumansInflammationInterleukin-6LipopolysaccharidesMiceNF-kappa BTumor Necrosis Factor-alphaCasein Kinase IIInterleukin-6LipopolysaccharidesMicroRNAsNF-kappa BTumor Necrosis Factor-alpha

Identifiers

PMID35832651
PMCPMC9273410

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.