Evidence map›Paper›PMID 35832590›Full record

ArticleFrontiers in pediatrics2022

Case Report: Anterior Scleritis Presenting as a Primary Ocular Manifestation in Multisystem Inflammatory Syndrome in Children With COVID-19.

Daisuke Matsubara, Daisuke Tamura, Yuka Kasuya, Yoshitaka Mizobe, Mami Hiwada, Mitsuru Seki, Shinji Makino, Takanori Yamagata

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Review of Ophthalmic Symptoms in COVID-19.Clinical ophthalmology (Auckland, N.Z.) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daisuke MatsubaraDepartment of Pediatrics, Jichi Medical University, Shimotsuke, Japan.
Daisuke TamuraDepartment of Pediatrics, Jichi Medical University, Shimotsuke, Japan.
Yuka KasuyaDepartment of Ophthalmology, Jichi Medical University, Shimotsuke, Japan.
Yoshitaka MizobeDepartment of Pediatrics, Jichi Medical University, Shimotsuke, Japan.
Mami HiwadaDepartment of Pediatrics, Jichi Medical University, Shimotsuke, Japan.
Mitsuru SekiDepartment of Pediatrics, Jichi Medical University, Shimotsuke, Japan.
Shinji MakinoDepartment of Ophthalmology, Jichi Medical University, Shimotsuke, Japan.
Takanori YamagataDepartment of Pediatrics, Jichi Medical University, Shimotsuke, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a newly defined hyperinflammatory disease linked to antecedent coronavirus disease 2019. Patients with MIS-C present with various symptoms, and ocular findings such as mild bilateral conjunctivitis are relatively common. However, detailed descriptions of severe ocular reports associated with MIS-C are scarce in the current literature. Here we report a case of MIS-C in a Japanese boy, with severe eye manifestations in the form of anterior scleritis as the primary MIS-C symptom. Detailed ocular examinations by ophthalmologists may be key for clarifying the pathophysiology of MIS-C.

Indexed as

case reportconjunctivitisCOVID-19fundus findingsKawasaki diseasemultisystem inflammatory syndrome in childrenophthalmological examinationsscleritis

Identifiers

PMID35832590
PMCPMC9271790

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.