Evidence map›Paper›PMID 35832378›Full record

ArticleFrontiers in cellular and infection microbiology2022

Proteomic and Functional Analysis of the Effects of Quinoxaline Derivatives on

Rodolfo Gamaliel Avila-Bonilla, Ángel López-Sandoval, Jacqueline Soto-Sánchez, Laurence A Marchat, Gildardo Rivera, Oscar Medina-Contreras, Esther Ramírez-Moreno

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Redox Proteomic Profile of Tirapazamine-Resistant Murine Hepatoma Cells.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rodolfo Gamaliel Avila-BonillaInstituto Politécnico Nacional, Escuela Nacional de Medicina y Homeopatía, Laboratorio de Biomedicina Molecular 2, México City, Mexico.
Ángel López-SandovalInstituto Politécnico Nacional, Escuela Nacional de Medicina y Homeopatía, Laboratorio de Biomedicina Molecular 2, México City, Mexico.
Jacqueline Soto-SánchezInstituto Politécnico Nacional, Escuela Nacional de Medicina y Homeopatía, Laboratorio de Biomedicina Molecular 2, México City, Mexico.
Laurence A MarchatInstituto Politécnico Nacional, Escuela Nacional de Medicina y Homeopatía, Laboratorio de Biomedicina Molecular 2, México City, Mexico.
Gildardo RiveraInstituto Politécnico Nacional, Centro de Biotecnología Genómica, Laboratorio de Biotecnología Farmacéutica, Reynosa, Mexico.
Oscar Medina-ContrerasHospital Infantil de México Federico Gómez, Unidad de Investigación Epidemiológica en Endocrinología y Nutrición (UIEEN), México City, Mexico.
Esther Ramírez-MorenoInstituto Politécnico Nacional, Escuela Nacional de Medicina y Homeopatía, Laboratorio de Biomedicina Molecular 2, México City, Mexico.
Instituto Politécnico Nacional · MXHospital Infantil de México Federico Gómez · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quinoxalines are heterocyclic compounds that contain a benzene ring and a pyrazine ring. The oxidation of both nitrogen of the pyrazine ring results in quinoxaline derivatives (QdNO), which exhibit a variety of biological properties, including antiparasitic activity. However, its activity against

Indexed as

Entamoeba histolyticaAnimalsHumansProteomicsPyrazinesQuinoxalinesReactive Oxygen SpeciesThioredoxin-Disulfide ReductaseTrophozoitesPyrazinesQuinoxalinesReactive Oxygen SpeciesThioredoxin-Disulfide ReductaseAntiamoebic activityE. histolyticafunctional analysisproteomicsquinoxaline derivatives

Identifiers

PMID35832378
PMCPMC9271875
OpenAlexW4283583777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.