Evidence map›Paper›PMID 35832322›Full record

ArticleRespirology case reports2022

Cytomegalovirus pneumonia in a background of central nervous system tuberculosis.

Sugeesha Wickramasinghe, Menaka Tillekeratne, Sasanka Wijayawardhana, Aflah Sadikeen, Dilshan Priyankara, Manoj Edirisooriya, Amitha Fernando

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respirology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Sugeesha WickramasingheDepartment of Respiratory Medicine Central Chest Clinic Borella Sri Lanka.ORCID https://orcid.org/0000-0001-6372-3263
Menaka TillekeratneDepartment of Respiratory Medicine Central Chest Clinic Borella Sri Lanka.
Sasanka WijayawardhanaDepartment of Respiratory Medicine Central Chest Clinic Borella Sri Lanka.
Aflah SadikeenDepartment of Respiratory Medicine Central Chest Clinic Borella Sri Lanka.
Dilshan PriyankaraDepartment of Critical Care National Hospital of Sri Lanka Borella Sri Lanka.
Manoj EdirisooriyaDepartment of Critical Care National Hospital of Sri Lanka Borella Sri Lanka.
Amitha FernandoDepartment of Respiratory Medicine Central Chest Clinic Borella Sri Lanka.
Teaching Hospital Kandy · LKNational Hospital of Sri Lanka · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 32-year-old patient, who was on treatment for tuberculous meningitis complicated with venous sinus thrombosis, was referred to the medical unit as he developed new onset fever, cough and shortness of breath. He was in respiratory distress and needed intubation. Investigations revealed elevated liver enzymes, leukopenia, spherocytosis and lower lobe predominant consolidations and diffuse nodules in the high-resolution computed tomography. He was suspected to have cytomegalovirus (CMV) pneumonia with the above results, and further investigations revealed an extremely elevated CMV viral load. He was treated with ganciclovir followed by valganciclovir for a total of 42 days resulting in a complete recovery. Liver functions resolved with anti-viral treatment, and he was started on full anti-tuberculosis (TB) treatment. Further investigations did not reveal evidence of immunosuppression. Association of CMV and TB is explained genetically, although clinical association is rarely described. The presence of either infection should lead to higher degree of suspicion of the respective other condition in relevant clinical setting.

Indexed as

cytomegalovirusimmunocompetentpneumoniaspherocytesTB meningitis

Identifiers

PMID35832322
PMCPMC9263535
OpenAlexW4284975580

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.