Evidence map›Paper›PMID 35832090›Full record

ArticleTheranostics2022

FGFR blockade boosts T cell infiltration into triple-negative breast cancer by regulating cancer-associated fibroblasts.

Yushen Wu, Ziying Yi, Jie Li, Yuxian Wei, Rui Feng, Jiazhou Liu, Jiefeng Huang, Yuru Chen, Xiaoyu Wang, Jiazheng Sun and 10 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.

  1. Pooled it
  2. Review
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  8. Targeting the Barriers Driving Immune Exclusion.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 1 country.

Yushen WuChongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Ziying YiChongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Jie LiChongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Yuxian WeiDepartment of Endocrine and Breast Surgery, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Rui FengChongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Jiazhou LiuChongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Jiefeng HuangChongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Yuru ChenChongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Xiaoyu WangChongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Jiazheng SunDepartment of Endocrine and Breast Surgery, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Xuedong YinDepartment of Endocrine and Breast Surgery, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Yunhai LiDepartment of Endocrine and Breast Surgery, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Jingyuan WanDepartment of Pharmacology, Chongqing Medical University; Chongqing, 400016, China.
Li ZhangDepartment of Pathophysiology, Chongqing Medical University; Chongqing, 400016, China.
Jing HuangDepartment of Respiratory, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Huimin DuDepartment of Oncology, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Xiaoyi WangDepartment of Endocrine and Breast Surgery, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Qin LiDepartment of Oncology, Beijing Friendship Hospital, Capital Medical University; Beijing, 100050, China.
Guosheng RenChongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Hongzhong LiChongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University; Chongqing, 400016, China.
Chongqing Medical University · CNFirst People's Hospital of Chongqing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cancer-Associated FibroblastsReceptors, Fibroblast Growth FactorT-LymphocytesTriple Negative Breast NeoplasmsAnimalsCell Line, TumorHumansLymphocytes, Tumor-InfiltratingMiceProtein Kinase InhibitorsPyrazolesQuinoxalinesTumor MicroenvironmenterdafitinibProtein Kinase InhibitorsPyrazolesQuinoxalinesReceptors, Fibroblast Growth Factorbreast cancerFGFRfibroblastimmunotherapyVCAM-1

Identifiers

PMID35832090
PMCPMC9254240
OpenAlexW4285275680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.