Evidence map›Paper›PMID 35832070›Full record

ArticleTheranostics2022

Genome instability is associated with ethnic differences between Asians and Europeans in hepatocellular carcinoma.

Neslihan A Kaya, Jianbin Chen, Hannah Lai, Hechuan Yang, Liang Ma, Xiaodong Liu, Jacob Santiago Alvarez, Jin Liu, Axel M Hillmer, David Tai and 7 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 2 countries.

Neslihan A KayaGenome Institute of Singapore, Agency for Science, Technology and Research, Singapore, 138672, Singapore.
Jianbin ChenGenome Institute of Singapore, Agency for Science, Technology and Research, Singapore, 138672, Singapore.
Hannah LaiGenome Institute of Singapore, Agency for Science, Technology and Research, Singapore, 138672, Singapore.
Hechuan YangKey Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Liang MaKey Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Xiaodong LiuKey Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Jacob Santiago AlvarezGenome Institute of Singapore, Agency for Science, Technology and Research, Singapore, 138672, Singapore.
Jin LiuCentre for Quantitative Medicine, Program in Health Services and Systems Research, Duke-NUS Medical School, Singapore, 169857, Singapore.
Axel M HillmerInstitute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, 50937, Germany.
David TaiDivision of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Joe Yeong Poh ShengSingapore General Hospital, Singapore, 169608, Singapore.
Zheng HuCAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Yun Shen ChanGuangzhou Laboratory, Guangzhou International Bio Island, Guangzhou 510005, Guangdong Province, China.
Pierce K H ChowHepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
Yuguang MuSchool of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore.
Torsten WuestefeldGenome Institute of Singapore, Agency for Science, Technology and Research, Singapore, 138672, Singapore.
Weiwei ZhaiGenome Institute of Singapore, Agency for Science, Technology and Research, Singapore, 138672, Singapore.
Agency for Science, Technology and Research · SGInstitute of Zoology · CNChinese Academy of Sciences · CNDuke-NUS Medical School · SGNanyang Technological University · SGSingapore General Hospital · SGGenome Institute of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is one of the deadliest cancer types with diverse etiological factors across the world. Although large scale genomic studies have been conducted in different countries, integrative analysis of HCC genomes and ethnic comparison across cohorts are lacking.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAsian PeopleBiomarkers, TumorGenomic InstabilityHumansBiomarkers, Tumor

Identifiers

PMID35832070
PMCPMC9254249
OpenAlexW4285118503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.