Evidence map›Paper›PMID 35832033›Full record

ArticleAging2022

Red blood cell distribution width in different time-points of peripheral thrombolysis period in acute ischemic stroke is associated with prognosis.

Mingli He, Hongrui Wang, Yi Tang, Bing Cui, Bingchao Xu, Xiaoqin Niu, Yongan Sun, Guanghui Zhang, Xiaobing He, Bei Wang and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Mingli HeDepartment of Neurology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Jiangsu, China.
Hongrui WangState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yi TangDepartment of Neurology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Jiangsu, China.
Bing CuiState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Bingchao XuDepartment of Neurology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Jiangsu, China.
Xiaoqin NiuDepartment of Neurology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Jiangsu, China.
Yongan SunDepartment of Neurology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Jiangsu, China.
Guanghui ZhangDepartment of Neurology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Jiangsu, China.
Xiaobing HeDepartment of Neurology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Jiangsu, China.
Bei WangDepartment of Neurology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Jiangsu, China.
Bei XuDepartment of Neurology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Jiangsu, China.
Zaipo LiDepartment of Neurology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Jiangsu, China.
Yu ZhangState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yibo WangState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xuzhou Medical College · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNLianyungang Oriental Hospital · CNPeking Union Medical College Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between red blood cell distribution width (RDW) in peripheral thrombolysis period and prognosis is not fully clarified in those who underwent intravenous thrombolysis (IVT) for acute ischemic stroke (AIS). Our study aimed to clarify this issue. A retrospective analysis of about 510 consecutive thrombolysis cases for AIS from January 2015 to March 2019 in a single-center database was done and followed-up for 3 months. We used univariate and multivariable models to evaluate the relationship between RDW levels at various time-points after IVT and the occurrence risk of hemorrhagic transformation (HT) and recurrent stroke, and used COX regression to assess the hazard ratios of outcomes with RDW levels. Elevated risk of HT was found in higher tertiles of RDW (OR = 10.282, 95% confidence interval (CI) 2.841-39.209,

Indexed as

Ischemic StrokeStrokeErythrocytesHumansPrognosisRetrospective StudiesThrombolytic Therapyacute ischemic strokeintracerebral hemorrhagerecurrent strokered blood cell distribution widththrombolysis

Identifiers

PMID35832033
PMCPMC9365566
OpenAlexW4285085534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.