Evidence map›Paper›PMID 35831783›Full record

Observational studyBMC geriatrics2022

Pharmacist-led medication reconciliation at patient discharge: a tool to reduce healthcare utilization? an observational study in patients 65 years or older.

Emma Bajeux, Lilian Alix, Lucie Cornée, Camille Barbazan, Marion Mercerolle, Jennifer Howlett, Vincent Cruveilhier, Charlotte Liné-Iehl, Bérangère Cador, Patrick Jego and 7 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04018781 (Eval CONPARMED Haute-Bretagne), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04018781 completednot on this map

Eval CONPARMED Haute-Bretagne : Guaranteeing the Continuity of the Care Pathway for the Elderly Patient: Evaluation of a Territorial Approach of Clinical Pharmacy

TypeobservationalSponsorRennes University HospitalRan2019 to 2020Enrolled443ConditionsMedication Reconciliation at DischargeArmsmedication reconciliation
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 2 countries.

Emma BajeuxDepartment of Epidemiology and Public Health, Univ Rennes, Rennes University Hospital, F-35000, Rennes, France. Emma.bajeux@chu-rennes.fr.
Lilian AlixDepartment of Internal Medicine and Clinical Immunology, Univ Rennes, Rennes University Hospital, F-35000, Rennes, France.
Lucie CornéeDepartment of Geriatrics, St-Laurent Polyclinic, Hospitalité St-Thomas de Villeneuve, F-35000, Rennes, France.
Camille BarbazanDepartment of Pharmacy, Rennes University Hospital, F-35000, Rennes, France.
Marion MercerolleDepartment of Pharmacy, Rennes University Hospital, F-35000, Rennes, France.
Jennifer HowlettDepartment of Pharmacy, Rennes University Hospital, F-35000, Rennes, France.
Vincent CruveilhierDepartment of Pharmacy, Fougères Hospital, F-35300, Fougères, France.
Charlotte Liné-IehlDepartment of Pharmacy, Montfort/Meu Hospital, F-35160, Montfort/Meu, France.
Bérangère CadorDepartment of Internal Medicine and Clinical Immunology, Univ Rennes, Rennes University Hospital, F-35000, Rennes, France.
Patrick JegoDepartment of Internal Medicine and Clinical Immunology, Univ Rennes, Rennes University Hospital, F-35000, Rennes, France.
Vincent GicquelDepartment of Pharmacy, Rennes University Hospital, F-35000, Rennes, France.
François-Xavier SchweyerDepartment of Human and Social Sciences, Univ Rennes, EHESP, EA7348 MOS, F-35000, Rennes, France.
Vanessa MarieFrance Asso Santé, F-35000, Rennes, France.
Stéphanie HamonicDepartment of Epidemiology and Public Health, Univ Rennes, Rennes University Hospital, F-35000, Rennes, France.
Jean-Michel JosselinUniv Rennes, CNRS, CREM-UMR 6211, F-35000, Rennes, France.
Dominique SommeDepartment of Geriatrics, Department of Geriatrics, Univ Rennes, EHESP, CNRS, Inserm, Arènes - UMR 6051, RSMS - U 1309 , F-35000, Rennes, France.
Benoit HueDepartment of Pharmacy, Rennes University Hospital, F-35000, Rennes, France.
Centre Hospitalier Universitaire de Rennes · FRUniversité de Rennes · FRCentre de Recherche en Économie et Management · FRCentre Hospitalier de Fougères · FRÉcole des Hautes Études en Santé Publique · FRInstitut des Sciences Humaines et Sociales · FRMontfort Hospital · CASaint Laurent Polyclinique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOlder patients often experience adverse drug events (ADEs) after discharge that may lead to unplanned readmission. Medication Reconciliation (MR) reduces medication errors that lead to ADEs, but results on healthcare utilization are still controversial. This study aimed to assess the effect of MR at discharge (MRd) provided to patients aged over 65 on their unplanned rehospitalization within 30 days and on both patients' experience of discharge and their knowledge of their medication.

methodsAn observational multicenter prospective study was conducted in 5 hospitals in Brittany, France.

resultsPatients who received both MR on admission (MRa) and MRd did not have significantly fewer deaths, unplanned rehospitalizations and/or emergency visits related to ADEs (OR = 1.6 [0.7 to 3.6]) or whatever the cause (p = 0.960) 30 days after discharge than patients receiving MRa alone. However, patients receiving both MRa and MRd were more likely to feel that their discharge from the hospital was well organized (p = 0.003) and reported more frequently that their community pharmacist received information about their hospital stay (p = 0.036).

conclusionsThis study found no effect of MRd on healthcare utilization 30 days after discharge in patients over 65, but the process improved patients' experiences of care continuity. Further studies are needed to better understand this positive impact on their drug care pathway in order to improve patients' ownership of their drugs, which is still insufficient. Improving both the interview step between pharmacist and patient before discharge and the transmission of information from the hospital to primary care professionals is needed to enhance MR effectiveness.

trial registrationNCT04018781 July 15, 2019.

Indexed as

Medication ReconciliationPatient Acceptance of Health CarePatient DischargeAgedDrug-Related Side Effects and Adverse ReactionsHumansPatient ReadmissionPharmacistsProspective StudiesAdverse Drug EventDischargeExperienceMedication ReconciliationOlder people

Identifiers

PMID35831783
PMCPMC9281036
OpenAlexW4285391752

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.