Evidence map›Paper›PMID 35831714›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2022

Preclinical and first-in-human evaluation of

Ming Zhou, Xiaobo Wang, Bei Chen, Shijun Xiang, Wanqian Rao, Zhe Zhang, Huanhuan Liu, Jianyang Fang, Xiaoqin Yin, Pengbo Deng and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Review
  7. Preclinical and first‑in‑human evaluation of [European journal of nuclear medicine and molecular imaging · 2025
    Article
  8. Structure-activity relationship ofEJNMMI radiopharmacy and chemistry · 2025
    Article
  9. Article
  10. Radiopharmaceuticals and their applications in medicine.Signal transduction and targeted therapy · 2025
    Review
  11. Review
  12. Article
  13. [European journal of nuclear medicine and molecular imaging · 2024
    Article
  14. Article
  15. Application ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  16. Article
  17. Article
  18. PET imaging of PD-L1 with a small molecule radiotracer.European journal of nuclear medicine and molecular imaging · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Ming Zhou *Department of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China.
Xiaobo Wang *Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, 4221-116 Xiang'an South Rd., Xiamen, 361102, China.
Bei Chen *Department of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China.
Shijun XiangDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China.
Wanqian RaoDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China.
Zhe ZhangCenter for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, 4221-116 Xiang'an South Rd., Xiamen, 361102, China.
Huanhuan LiuCenter for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, 4221-116 Xiang'an South Rd., Xiamen, 361102, China.
Jianyang FangCenter for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, 4221-116 Xiang'an South Rd., Xiamen, 361102, China.
Xiaoqin YinDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China.
Pengbo DengDepartment of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China.
Xianzhong ZhangCenter for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, 4221-116 Xiang'an South Rd., Xiamen, 361102, China. zhangxzh@xmu.edu.cn.
Shuo HuDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China. hushuo2018@163.com.ORCID 0000-0003-0998-8943
Central South University · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePD-L1 PET imaging allows for the whole body measuring its expression across primary and metastatic tumors and visualizing its spatiotemporal dynamics before, during, and after treatment. In this study, we reported a novel

methodsManual and automatic radiosynthesis of

resultsThe radiosynthesis of

conclusion

Indexed as

B7-H1 AntigenFluorine RadioisotopesCell Line, TumorFluorodeoxyglucose F18HumansPeptidesPositron-Emission TomographyPositron Emission Tomography Computed TomographyTissue DistributionB7-H1 AntigenFluorine RadioisotopesFluorodeoxyglucose F18PeptidesD-Peptide antagonistImmune checkpointsPD-1/PD-L1PET imaging

Identifiers

PMID35831714
OpenAlexW4285391140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.