Evidence map›Paper›PMID 35831698›Full record

ArticleInternational journal of behavioral medicine2023

Distress Disorder Histories Relate to Greater Physical Symptoms Among Breast Cancer Patients and Survivors: Findings Across the Cancer Trajectory.

Megan E Renna, M Rosie Shrout, Annelise A Madison, Maryam Lustberg, Stephen P Povoski, Doreen M Agnese, Raquel E Reinbolt, Robert Wesolowski, Nicole O Williams, Bhuvaneswari Ramaswamy and 8 more

Open access · greenAbstract read
In one paragraph

Article in International journal of behavioral medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Caregiving responsibility and psychological distress among community-dwelling cancer survivors in the United States.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Megan E RennaSchool of Psychology, University of Southern Mississippi, 118 College Drive #5025, Hattiesburg, MS, 39406, USA. megan.renna@usm.edu.ORCID http://orcid.org/0000-0003-3941-4270
M Rosie ShroutPurdue University, West Lafayette, USA.ORCID http://orcid.org/0000-0001-5751-1782
Annelise A MadisonThe Ohio State University, Columbus, USA.ORCID http://orcid.org/0000-0001-6091-6844
Maryam LustbergYale School of Medicine, New Haven, USA.ORCID http://orcid.org/0000-0001-8559-5645
Stephen P PovoskiThe Ohio State University College of Medicine, Columbus, USA.ORCID http://orcid.org/0000-0002-3419-2763
Doreen M AgneseThe Ohio State University College of Medicine, Columbus, USA.ORCID http://orcid.org/0000-0002-9910-9422
Raquel E ReinboltThe Ohio State University College of Medicine, Columbus, USA.ORCID http://orcid.org/0000-0002-1250-2222
Robert WesolowskiThe Ohio State University College of Medicine, Columbus, USA.ORCID http://orcid.org/0000-0003-0606-0648
Nicole O WilliamsThe Ohio State University College of Medicine, Columbus, USA.
Bhuvaneswari RamaswamyThe Ohio State University College of Medicine, Columbus, USA.ORCID http://orcid.org/0000-0002-2822-8379
Sagar D SardesaiThe Ohio State University College of Medicine, Columbus, USA.ORCID http://orcid.org/0000-0002-4648-4018
Anne M NoonanThe Ohio State University College of Medicine, Columbus, USA.ORCID http://orcid.org/0000-0001-8083-8492
Jeffrey B VanDeusenThe Ohio State University College of Medicine, Columbus, USA.ORCID http://orcid.org/0000-0002-4171-5649
Daniel G StoverThe Ohio State University College of Medicine, Columbus, USA.ORCID http://orcid.org/0000-0001-9003-8165
Mathew CherianThe Ohio State University College of Medicine, Columbus, USA.ORCID http://orcid.org/0000-0002-0380-2012
William B MalarkeyThe Ohio State University College of Medicine, Columbus, USA.ORCID http://orcid.org/0000-0002-8817-9265
Michael Di GregorioThe Ohio State University College of Medicine, Columbus, USA.
Janice K Kiecolt-GlaserThe Ohio State University College of Medicine, Columbus, USA.ORCID http://orcid.org/0000-0003-4900-9578
The Ohio State University · USPurdue University West Lafayette · USUniversity of Southern Mississippi · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Tracking and Evaluation CoreU54GM115428 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI GRANGER, JOEY P. · 2016 to 2025
$38.2M
Breast Cancer Survivors Cardiovascular Risks: Treatment and Behavioral InfluencesR01CA186720 · NCI · OHIO STATE UNIVERSITY · PI KIECOLT-GLASER, JANICE · 2014 to 2018
$4.6M
Aerobic Capacity, Depression, & Inflammatory Responsivity in Cancer SurvivorsR01CA186251 · NCI · OHIO STATE UNIVERSITY · PI KIECOLT-GLASER, JANICE · 2015 to 2019
$3.1M
Training Program For Cancer Prevention and ControlT32CA229114 · NCI · OHIO STATE UNIVERSITY · PI Chyke Abadama Doubeni, Peter G. Shields · 2018 to 2026
$2.0M
NRSA Training CoreTL1TR002735 · NCATS · OHIO STATE UNIVERSITY · PI BUMGARDNER, GINNY L, KIRSCHNER, LAWRENCE S · 2018 to 2022
$1.3M
NCATS NIH HHS TL1 TR002735NCATS NIH HHS UL1 TR001863NCI NIH HHS R01 CA186251NCI NIH HHS R01CA186251NCI NIH HHS R01 CA186720NCI NIH HHS R01CA186720NCI NIH HHS T32 CA229114NIGMS NIH HHS U54 GM115428NIH HHS TL1TR002735
6 · The paper itself

Abstract

backgroundPsychological disorders can substantially worsen physical symptoms associated with breast cancer diagnosis and treatment, reducing survivors' quality of life and increasing recurrence risk. Distress disorders may be particularly detrimental given their physical correlates. Across two studies, we examined the relationship between a distress disorder history and physical symptoms pre- and post-adjuvant treatment - two important periods of the cancer trajectory.

methodsBreast cancer patients awaiting adjuvant treatment (n = 147; mean age = 52.54) in study 1 and survivors 1-10 years post-treatment (n = 183; mean age = 56.11) in study 2 completed a diagnostic interview assessing lifetime presence of psychological disorders. They also rated their pain, fatigue, physical functioning, and self-rated health. Covariates included body mass index, age, cancer stage, menopause status, and physical comorbidities.

resultsResults from both studies indicated that a distress disorder history was associated with higher pain, fatigue, and sleep difficulties as well as lower self-rated health compared to those without such a history.

conclusionsThese findings suggest that breast cancer survivors with a distress disorder may be particularly at risk for more physical symptoms, poorer sleep, and worse self-rated health both prior to and following adjuvant treatment.

Indexed as

Breast NeoplasmsAnxietyFatigueFemaleHumansMiddle AgedPainQuality of LifeSurvivorsAnxietyBreast cancerDepressionFatiguePain

Identifiers

PMID35831698
PMCPMC10278051
OpenAlexW4285391683

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.