Evidence map›Paper›PMID 35831694›Full record

ArticleBiological trace element research2023

Oxidative Stress and Neurotoxicity of Cadmium and Zinc on Artemia franciscana.

Biljana Kukavica, Biljana Davidović-Plavšić, Ana Savić, Dejan Dmitrović, Goran Šukalo, Sandra Đurić-Savić, Goran Vučić

Abstract read
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In one paragraph

Article in Biological trace element research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Biljana KukavicaDepartmant of Biology, Faculty of Natural Sciences and Mathematics, University of Banja Luka, Banja Luka, Bosnia and Herzegovina. biljana.kukavica@pmf.unibl.org.ORCID http://orcid.org/0000-0003-1530-0391
Biljana Davidović-PlavšićDepartmant of Chemistry, Faculty of Natural Sciences and Mathematics, University of Banja Luka, Banja Luka, Bosnia and Herzegovina.ORCID http://orcid.org/0000-0001-8846-6494
Ana SavićDepartment of Biology and Ecology, Faculty of Sciences and Mathematics, University of Niš, Niš, Serbia.ORCID http://orcid.org/0000-0002-1327-5498
Dejan DmitrovićDepartmant of Biology, Faculty of Natural Sciences and Mathematics, University of Banja Luka, Banja Luka, Bosnia and Herzegovina.ORCID http://orcid.org/0000-0001-9134-3276
Goran ŠukaloDepartmant of Biology, Faculty of Natural Sciences and Mathematics, University of Banja Luka, Banja Luka, Bosnia and Herzegovina.ORCID http://orcid.org/0000-0003-0217-9772
Sandra Đurić-SavićMiloš Dujić Elementary School, Čelinac, Bosnia and Herzegovina.ORCID http://orcid.org/0000-0003-0264-8970
Goran VučićFaculty of Technology, University of Banja Luka, Banja Luka, Bosnia and Herzegovina.ORCID http://orcid.org/0000-0002-5582-8556
University of Banja Luka · BAUniversity of Nis · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite not being redox-active metals, Cd and Zn can disrupt cellular redox homeostasis by acting pro-oxidatively. The aim of this study was to examine the effects of exposure to Zn (14 and 72 mg/L) and Cd (7.7 and 77 mg/L) for 24 and 48 h on oxidative and antioxidative parameters and the activity of glutathione-S-transferase in Artemia franciscana tissue. In addition, the neurotoxicity of the metals was examined by determining the activity of acetylcholinesterase (AChE). In A. franciscana tissue, Cd (0.0026 ± 0.0001 mg/L) was detected only after 48 h of exposure to 77 mg/L Cd. After 24 h, the 14- and 72-mg/L Zn treatments resulted in significant increases in the Zn concentration (0.54 ± 0.026 mg/L (p < 0.01) and 0.68 ± 0.035 (p < 0.0001), respectively) in A. franciscana tissue compared with the control level, and significant increases were also detected after 48 h (0.59 ± 0.02 (p < 0.0001) and 0.79 ± 0.015 (p < 0.0001), respectively). The malondialdehyde (MDA) concentration in the metal-treated samples was increased after 24 h of exposure, whereas after 48 h, an increase in the MDA concentration was detected only with 7.7. mg/L Cd. A significant increase in the H

Indexed as

CadmiumZincAcetylcholinesteraseAnimalsArtemiaCatalaseHydrogen PeroxideOxidative StressSuperoxide DismutaseAcetylcholinesteraseCadmiumCatalaseHydrogen PeroxideSuperoxide DismutaseZincAcetylcholinesteraseAntioxidative metabolismBiotransformationCatalaseGlutathioneHeavy metalsOxidative stressSuperoxide dismutase

Identifiers

PMID35831694
OpenAlexW4285394896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.