Evidence map›Paper›PMID 35831485›Full record

ArticleFish physiology and biochemistry2022

Metabolomics analysis of the potential toxicological mechanisms of diquat dibromide herbicide in adult zebrafish (Danio rerio) liver.

Ye Xiao, Xiang Lin, Meilan Zhou, Tianyu Ren, Ruili Gao, Zhongqun Liu, Wenjing Shen, Rong Wang, Xi Xie, Yanting Song and 1 more

Abstract read
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In one paragraph

Article in Fish physiology and biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. [A Preliminary Study on the Plasma Metabolomic Profiles of Patients Suffering From Acute Diquat Poisoning].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Ye Xiao *School of Pharmaceutical Sciences, Hainan University, 58 Renmin Rd, Haikou, 570228, People's Republic of China.
Xiang Lin *School of Pharmaceutical Sciences, Hainan University, 58 Renmin Rd, Haikou, 570228, People's Republic of China.
Meilan ZhouSchool of Pharmaceutical Sciences, Hainan University, 58 Renmin Rd, Haikou, 570228, People's Republic of China.
Tianyu RenSchool of Pharmaceutical Sciences, Hainan University, 58 Renmin Rd, Haikou, 570228, People's Republic of China.
Ruili GaoSchool of Pharmaceutical Sciences, Hainan University, 58 Renmin Rd, Haikou, 570228, People's Republic of China.
Zhongqun LiuSchool of Pharmaceutical Sciences, Hainan University, 58 Renmin Rd, Haikou, 570228, People's Republic of China.
Wenjing ShenSchool of Pharmaceutical Sciences, Hainan University, 58 Renmin Rd, Haikou, 570228, People's Republic of China.
Rong WangSchool of Pharmaceutical Sciences, Hainan University, 58 Renmin Rd, Haikou, 570228, People's Republic of China.
Xi XieSchool of Pharmaceutical Sciences, Hainan University, 58 Renmin Rd, Haikou, 570228, People's Republic of China.
Yanting SongSchool of Pharmaceutical Sciences, Hainan University, 58 Renmin Rd, Haikou, 570228, People's Republic of China.
Wenting HuSchool of Pharmaceutical Sciences, Hainan University, 58 Renmin Rd, Haikou, 570228, People's Republic of China. HuWT_0@hainanu.edu.cn.
Hainan University · CN

Funding

National Natural Science Foundation of China 31902418Natural Science Foundation of Hainan Province 319QN160Research Initiation Fund Project of Hainan University KYQD(ZR)19108
6 · The paper itself

Abstract

Although diquat is a widely used water-soluble herbicide in the world, its sublethal adverse effects to fish have not been well characterised. In this study, histopathological examination and biochemical assays were applied to assess hepatotoxicity and combined with gas chromatography-mass spectrometry (GC-MS)-based metabolomics analysis to reveal overall metabolic mechanisms in the liver of zebrafish (Danio rerio) after diquat exposure at concentrations of 0.34 and 1.69 mg·L

Indexed as

HerbicidesWater Pollutants, ChemicalAnimalsDiquatEmbryo, NonmammalianLiverZebrafishDiquatHerbicidesWater Pollutants, ChemicalDiquatHepatotoxicityMetabolomicsZebrafish

Identifiers

PMID35831485
OpenAlexW4285084596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.