Evidence map›Paper›PMID 35831440›Full record

ArticleScientific reports2022

Domination based classification algorithms for the controllability analysis of biological interaction networks.

Stephen K Grady, Faisal N Abu-Khzam, Ronald D Hagan, Hesam Shams, Michael A Langston

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. A graph theoretical approach to experimental prioritization in genome-scale investigations.Mammalian genome : official journal of the International Mammalian Genome Society · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Stephen K GradyGraduate School of Genome Science and Technology, University of Tennessee, Knoxville, TN, USA. sgrady3@vols.utk.edu.
Faisal N Abu-KhzamDepartment of Computer Science and Mathematics, Lebanese American University, Beirut, Lebanon.
Ronald D HaganDepartment of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN, USA.
Hesam ShamsDepartment of Industrial and Systems Engineering, University of Tennessee, Knoxville, TN, USA.
Michael A LangstonDepartment of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN, USA.
University of Tennessee at Knoxville · USLebanese American University · LB

Funding

Data Structures, Algorithms and Tools for Ontological DiscoveryR01AA018776 · NIAAA · JACKSON LABORATORY · PI CHESLER, ELISSA J · 2010 to 2019
$3.9M
Pregnancy-Associated MortalityR01HD092653 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI WALLACE, MAEVE E · 2018 to 2022
$1.6M
EPA G17D112354237NIAAA NIH HHS R01 AA018776NICHD NIH HHS R01 HD092653NIH HHS R01AA018776
6 · The paper itself

Abstract

Deciding the size of a minimum dominating set is a classic NP-complete problem. It has found increasing utility as the basis for classifying vertices in networks derived from protein-protein, noncoding RNA, metabolic, and other biological interaction data. In this context it can be helpful, for example, to identify those vertices that must be present in any minimum solution. Current classification methods, however, can require solving as many instances as there are vertices, rendering them computationally prohibitive in many applications. In an effort to address this shortcoming, new classification algorithms are derived and tested for efficiency and effectiveness. Results of performance comparisons on real-world biological networks are reported.

Indexed as

AlgorithmsProteinsProteins

Identifiers

PMID35831440
PMCPMC9279401
OpenAlexW4285392667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.