ArticleCanadian family physician Medecin de famille canadien2022
Erythema multiforme in children.
Article in Canadian family physician Medecin de famille canadien, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- More than Mucositis: Pediatric RIME Following Co-Infection with SARS-CoV-2 andInfectious disease reports · 2025Article
- Common Skin Conditions in Older Infants and Toddlers.Indian journal of pediatrics · 2025Review
- Targetoid skin lesions in a newborn: a case of erythema multiforme.Oxford medical case reports · 2024Article
- Recent findings on drug hypersensitivity in children.Frontiers in allergy · 2024Review
- Urticaria: A Narrative Overview of Differential Diagnosis.Biomedicines · 2023Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
questionChildren who present with rashes with "target" lesions are frequently diagnosed with erythema multiforme (EM). This is a self-limiting condition in most children; how should primary care providers differentiate between this and urticaria or Stevens-Johnson syndrome, and what is the recommended course of treatment? ANSWER: While EM is common in children, urticaria is also very common and tends to be more "waxing and waning" compared with EM's fixed lesions. Stevens-Johnson syndrome and toxic epidermal necrolysis are more severe and distinct conditions; they have much more substantial mucous membrane involvement and contain widespread erythematous or purpuric macules with blisters. Since EM is a self-limiting condition, treatment of EM in children is generally supportive, and rarely do children need hospital admission for rehydration. In more severe cases involving mucous membranes or substantial pain, some patients will benefit from topical steroids or antihistamines. When children present with signs of herpes infection, antiviral treatment (acyclovir) may be of benefit. Systemic steroids should be reserved for the most challenging cases.
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Registered trials
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